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MetabolomicsHypoxia Dependent Inhibition of Glioblastoma Cell Proliferation, Invasion, and Metabolism by the Choline-Kinase Inhibitor JAS239
Background: Elevated choline kinase alpha (ChoK) levels are observed in most solid tumors, including glioblastomas (GBM), and ChoK inhibitors have demonstrated limited efficacy in GBM models. Given that hypoxia is associated with resistance to GBM therapy, we hypothesized that tumor hypoxia c...
2024-06-18 | MTBLS6212 | MetaboLights
UnknownImpact of endorectal filling on interobserver variability of MRI based rectal primary tumor delineation.
Not available
S-EPMC9589000 | biostudies-literature
UnknownUltrasound in active surveillance for low-risk papillary thyroid cancer: imaging considerations in case selection and disease surveillance.
Not available
S-EPMC8446145 | biostudies-literature
UnknownPotential Molecular Targets in the Setting of Chemoradiation for Esophageal Malignancies.
Not available
S-EPMC8600025 | biostudies-literature
TranscriptomicsGene expression-based, inflammatory response prediction by bronchial epithelial cell line treated with signal peptide of eosinophil cationic protein
Background Eosinophil cationic protein is a clinical asthma biomarker that would be released into blood, especially gathered in bronchia. The signal peptide of eosinophil cationic protein (ECPsp) plays an important role in translocating ECP to the extracellular space. We previously reported that ECP...
ORGANISM(S): Homo sapiens 
2013-07-20 | E-GEOD-39122 | biostudies-arrayexpress
UnknownSPTSSA variants alter sphingolipid synthesis and cause a complex hereditary spastic paraplegia.
Not available
S-EPMC10319774 | biostudies-literature
UnknownEfficacy and Safety of Nivolumab Plus Ipilimumab in Patients With Advanced Hepatocellular Carcinoma Previously Treated With Sorafenib: The CheckMate 040 Randomized Clinical Trial.
Not available
S-EPMC7530824 | biostudies-literature
UnknownIdentification of Risk Loci for Parkinson Disease in Asians and Comparison of Risk Between Asians and Europeans: A Genome-Wide Association Study.
Not available
S-EPMC7171584 | biostudies-literature
UnknownToronto Workshop on Late Recurrence in Estrogen Receptor-Positive Breast Cancer: Part 2: Approaches to Predict and Identify Late Recurrence, Research Directions.
Not available
S-EPMC7050024 | biostudies-literature
UnknownToronto Workshop on Late Recurrence in Estrogen Receptor-Positive Breast Cancer: Part 1: Late Recurrence: Current Understanding, Clinical Considerations.
Not available
S-EPMC7049988 | biostudies-literature
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