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ProteomicsTargeting the E2F1/GAS5/p53 Axis as a Potential Therapeutic Strategy for Gefitinib-Resistant Lung Cancer
Lung cancer is one of the most common and fatal cancer worldwide. There are two major types of lung cancer, non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). Recently, gefitinib, a small molecule, which target tyrosine kinase, has been regarded as the first-line treatment in NSCL...
ORGANISM(S): Homo sapiens (Human) 
2020-08-17 | PXD013139 | Pride
Lung cancer Ectopic atp synthase Lncrna-interactomics Gefitinib resistance 
ProteomicsQuantitative phosphoproteomics reveals the temporal phosphorylation network regulated via mesenchymal stem cells in the tumor microenvironment
The tumor microenvironment (TME), which comprises cellular and noncellular components, is involved in the complex process of cancer development. Emerging evidence suggests that mesenchymal stem cells (MSCs), one of the vital regulators of the TME, foster tumor progression through paracrine secretion...
ORGANISM(S): Homo sapiens (Human) 
2022-06-09 | PXD029288 | Pride
C-fos Phosphoproteomics Tumor microenvironment Mesenchymal stem cell Ectopic atp synthase Mapk P2x7r 
TranscriptomicsGrowth inhibition of ovarian tumor-initiating cells by niclosamide
The gene expression profile in treated CP70 side population spheroid cells (CP70sps cells) was analyzed to investigate the effect of niclosamide inhibition on ovarian tumor-initiating cells. CP70sps cells are isolated and characterized as one kind of ovarian tumor-initiating cells, and they show ste...
ORGANISM(S): Homo sapiens 
2012-08-05 | E-GEOD-36259 | biostudies-arrayexpress
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
UnknownElliptic anisotropy measurement of the f<sub>0</sub>(980) hadron in proton-lead collisions and evidence for its quark-antiquark composition.
Not available
S-EPMC12391314 | biostudies-literature
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