Sort   by:  
 Page size 
TranscriptomicsSmall RNA profile in E18.5 fetal liver from wild type and Ago2 catalytically inactive mutant mice
Examination of miRNAs in fetal liver revealed a loss of miR-451, a small RNA important for erythropoiesis. Total RNA was isolated and size-fractionated by PAGE into 19-30nt. These were processed and sequenced on Illumina GA2 platform.
ORGANISM(S): Mus musculus 
2010-05-05 | E-GEOD-21370 | biostudies-arrayexpress
TranscriptomicsCAF-1 safeguards somatic cell identity during factor-induced reprogramming
Cellular differentiation involves profound changes in the chromatic landscape, yet the mechanisms by which somatic cell identity is subsequently maintained remain incompletely understood. To further elucidate regulatory pathways that safeguard the somatic state, we performed two comprehensive RNAi ...
ORGANISM(S): Mus musculus 
2015-12-10 | E-GEOD-72741 | biostudies-arrayexpress
GenomicsThe histone chaperone CAF-1 safeguards somatic cell identity during transcription factor-induced reprogramming (sequencing)
During development, specialized cell lineages are generated through the establishment of cell type-specific transcriptional patterns and epigenetic programs. However, the precise mechanisms and regulators that maintain these specialized cell states remain largely elusive. To identify molecules that ...
ORGANISM(S): Mus musculus 
2015-12-10 | E-GEOD-72744 | biostudies-arrayexpress
TranscriptomicsThe histone chaperone CAF-1 safeguards somatic cell identity during transcription factor-induced reprogramming
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2015-12-10 | E-GEOD-66534 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling upon knockdown of the RNA-binding protein Unkempt
RNAseq to assess changes in transcript abundance upon knockdown of the RNA-binding protein Unkempt in human SH-SY5Y cell lines.
ORGANISM(S): Homo sapiens 
2015-01-15 | E-MTAB-2277 | biostudies-arrayexpress
GenomicsDefining a molecular roadmap of cellular reprogramming into iPS cells [ChIP-Seq]
Factor induced reprogramming is a slow and inefficient process with only rare cells progressing towards induced pluripotent stem cells (iPSCs). Owing to these restraints, mechanistic studies have been limited to analyses of heterogeneous bulk populations undergoing reprogramming and partially reprog...
ORGANISM(S): Mus musculus 
2012-12-20 | E-GEOD-42477 | biostudies-arrayexpress
TranscriptomicsDefining a molecular roadmap of cellular reprogramming into iPS cells [miRNA profiling]
Factor induced reprogramming is a slow and inefficient process with only rare cells progressing towards induced pluripotent stem cells (iPSCs). Owing to these restraints, mechanistic studies have been limited to analyses of heterogeneous bulk populations undergoing reprogramming and partially reprog...
ORGANISM(S): Mus musculus 
2012-12-20 | E-GEOD-42475 | biostudies-arrayexpress
TranscriptomicsDefining a molecular roadmap of cellular reprogramming into iPS cells [mRNA profiling]
Factor induced reprogramming is a slow and inefficient process with only rare cells progressing towards induced pluripotent stem cells (iPSCs). Owing to these restraints, mechanistic studies have been limited to analyses of heterogeneous bulk populations undergoing reprogramming and partially reprog...
ORGANISM(S): Mus musculus 
2012-12-20 | E-GEOD-42379 | biostudies-arrayexpress
Sort   by:  
 Page size