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MetabolomicsStage-specific metabolic responses in blue mussels to marine shipping-related acoustic and chemical stressors revealed by nuclear magnetic resonance

Maritime traffic exposes coastal organisms to both acoustic disturbance and chemical pollution, yet how these stressors affect and interact across early developmental stages remains poorly understood. We investigated stage-specific metabolic responses of blue mussel (Mytilus edulis) larv...

2026-06-15 | MTBLS13945 | MetaboLights
MetabolomicsComparison of Chemical Compositions in Pseudostellariae Radix from Different Cultivated Fields and Germplasms by NMR-Based Metabolomics
Pseudostellariae Radix (PR) is an important traditional Chinese medicine (TCM), which is consumed commonly for its positive health effects. However, the chemical differences of PR from different cultivated fields and germplasms are still unknown. In order to comprehensively compare the chemical comp...
2018-01-25 | MTBLS399 | MetaboLights
MetabolomicsThe timing of bacterial mesophyll infection shapes the leaf chemical landscape during the interaction

Chemistry in eukaryotic intercellular spaces is shaped by both hosts and symbiotic microorganisms such as bacteria. Pathogenic microorganisms like barley associated Xanthomonas translucens (Xt) swiftly overtake the inner leaf tissue becoming the dominant microbial community member during disease ...

2024-02-01 | MTBLS7676 | MetaboLights
MetabolomicsNext-generation biomonitoring of the early-life chemical exposome in neonatal and infant development

Exposure to synthetic and natural chemicals is a major environmental risk factor in the etiology of many chronic diseases. Investigating complex co-exposures is necessary for a holistic assessment in exposome-wide association studies. In this work, a sensitive liquid chromatography-tandem mass sp...

2023-10-26 | MTBLS2442 | MetaboLights
MetabolomicsA large-scale metabolomics study to harness chemical diversity and explore biochemical mechanisms in ryegrass (UPLC-MS HILIC POS assay)
Perennial ryegrass (Lolium perenne) is integral to temperate pastoral agriculture, which contributes most of the milk and meat production worldwide. Chemical profiles and diversity of ryegrass offer several opportunities to harness specific traits and elucidate underlying biological mechanism...
2019-03-01 | MTBLS62 | MetaboLights
MetabolomicsOptimizing peak picking and development of a suspect screening tool for rapid annotation of the human chemical exposome from LC- HRMS datasets
The technological advances of cutting-edge high-resolution mass spectrometry (HRMS) has set the stage for a new paradigm for exposure assessment. However, it is critical to ensure that bioinformatics software developed to process raw HRMS data can disentangle low-abundant xenobiotics from the noise....
2021-01-04 | MTBLS1785 | MetaboLights
ProteomicsChemical and Random Additive Noise Elimination (CRANE) - case_study - multicenter_dataset
The effectiveness of the novel electrospray ionisation - liquid chromatography mass spectrometry (ESI-LC-MS) data de-noising technique, CRANE, is demonstrated by denoising the MS1 and all the MS2 windows of the multicentre, data-independent acquisi-tion (DIA) MS dataset from Navarro, et al. (2016).
ORGANISM(S): Homo sapiens (Human) Escherichia coli Saccharomyces cerevisiae (Baker's yeast) 
2021-07-26 | PXD020529 | Pride
Lc-msms Random noise Chemical noise Denoise Baseline noise Dia 
TranscriptomicsTime-series transcriptome analysis of the older adult mouse cochlea after noise exposure
The aim of this experiment was to gain insights into temporal differences in gene expression following noise exposure in older adult mice with an average age of 17 months. Cochleae were collected at 24 hours, 72 hours and 1 week after noise exposure for subsequent RNA sequencing.
ORGANISM(S): Mus musculus 
2025-11-21 | E-MTAB-16125 | biostudies-arrayexpress
MetabolomicsMetabolomic evidence for biogeographic segregation in Espeletiinae (Asteraceae): A new perspective on an Andean adaptive radiation in sky islands (Intraspecific chemical variability assay)

The biogeography of tropical Andean plants and the effects of altitudinal barriers as evolutionary constraints have been the focus of great debate. Although genetic markers have provided evidence for the geographic isolation of Andean-endemic groups, even highly variable molecular markers commonl...

2020-03-24 | MTBLS943 | MetaboLights
MetabolomicsMetabolomic evidence for biogeographic segregation in Espeletiinae (Asteraceae): A new perspective on an Andean adaptive radiation in sky islands (Interspecific chemical variability assay)

The biogeography of tropical Andean plants and the effects of altitudinal barriers as evolutionary constraints have been the focus of great debate. Although genetic markers have provided evidence for the geographic isolation of Andean-endemic groups, even highly variable molecular markers commonl...

2020-03-24 | MTBLS944 | MetaboLights
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