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The capacity of planktonic marine microorganisms to actively seek out and exploit microscale chemical hotspots has been widely theorized to affect ocean-basin scale biogeochemistry, but has never been examined comprehensively in situ among natural microbial communities. Here, using a field-based ...

2022-02-15 | MTBLS1980 | MetaboLights
Gut microbiota dysbiosis and immune dysregulation are closely linked to colorectal cancer development. Identifying mechanistic connections among specific microbial species, metabolites, and immune responses may reveal novel insights into its pathogenesis. Here, employing metagenomic, metabolomic, an...
2026-05-20 | MTBLS14505 | MetaboLights
SPANXA2-OT1 promotes macrophage chemotaxis
Entomopathogenic nematodes (EPN) such as Steinernema spp. and Heterorhabditis spp. are obligate parasites of insects and effective biocontrol agents. Infective juveniles (IJs) of Steinernema carpocapsae and Heterorhabditis megidis are distantly related and exhibit different foraging behaviours but u...
ORGANISM(S): Escherichia coli Steinernema carpocapsae 
2022-11-09 | PXD027609 | Pride
Chemotaxis is a widespread strategy used by unicellular and multicellular living organisms to maintain their fitness in stressful environments. We previously showed that bacteria can trigger a negative chemotactic response to a copper (Cu)-rich environment. Cu ions toxicity on bacterial cell physiol...
ORGANISM(S): Bacteria Caulobacter vibrioides 
2023-09-05 | PXD044512 | Pride
The Toll-like receptor and chemotaxis pathways are key components of the innate immune system. Computational modeling and simulation at the molecular interaction level can be used to study complex biological pathways, but protein concentration values must be input as model parameters. In this invest...
ORGANISM(S): Mus Musculus 
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