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ProteomicsBAHCC1 binds H4K20me1 to facilitate the MCM complex loading for DNA replication
Methylation of histone H4 lysine 20 (H4K20), such as H4K20 mono-methylation (H4K20me1), regulates the biological processes of DNA replication, cell cycle progression, and DNA damage repair1-4. Whereas H4K20me1 is knowingly written by SET85,6 (also known as PR-Set7) and erased by PHF87 (also known as...
ORGANISM(S): Homo sapiens (Human) 
2025-06-06 | PXD036436 | Pride
Bioid Gelc Human Nsaf 
UnknownBAHCC1 binds H4K20me1 to facilitate the MCM complex loading and DNA replication.
Not available
S-EPMC12219854 | biostudies-literature
UnknownAssociation between regional body fat and cardiovascular disease risk among postmenopausal women with normal body mass index.
Not available
S-EPMC6933870 | biostudies-literature
ProteomicsCaspase-8’s non-apoptotic role is critical for orchestrating exaggerated inflammation during severe SARS-CoV-2 infection.
Excessive inflammation and cytokine release are hallmarks of severe COVID-19. Programmed cell death is known to drive inflammation, however, its relevance in the pathogenesis of severe COVID-19 is unclear. Using a combination of gene-targeted murine models and transcriptomic approaches we found that...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-20 | PXD057656 | Pride
Sars-cov-2  caspase-8  inflammation  flip  covid-19  cytokines 
UnknownPilot study of Tremelimumab with and without cryoablation in patients with metastatic renal cell carcinoma.
Not available
S-EPMC8569213 | biostudies-literature
ProteomicsPLpro inhibition protects in post-acute sequelae mouse model of COVID-19
The COVID-19 pandemic has highlighted how vulnerable a globally connected population is to the threat of newly emerging zoonotic viruses, exemplified by SARS-CoV-2. Despite considerable efforts to identify antivirals for coronaviruses (CoVs) in the last two decades, there exists only one FDA-approve...
ORGANISM(S): Mus musculus (Mouse) 
2025-02-23 | PXD054356 | Pride
Sars-cov-2  long covid  pasc  inflammation 
UnknownPrespecified dose-response analysis for A Very Early Rehabilitation Trial (AVERT).
Not available
S-EPMC4898313 | biostudies-literature
UnknownIntegrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance.
Not available
S-EPMC5819607 | biostudies-literature
UnknownEfficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine.
Not available
S-EPMC7787219 | biostudies-literature
UnknownGenomic and immune heterogeneity are associated with differential responses to therapy in melanoma.
Not available
S-EPMC5557036 | biostudies-literature
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