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Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent of COVID-19, has caused a worldwide pandemic since its discovery at the end of 2019. The spike (S) protein of SARS-CoV-2 is responsible for the host cell entry and the critical targets of the immune system. Consequentl...
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 
2021-03-24 | PXD023346 |
We collected 14 patients who tested positive for nasopharyngeal swab real-time PCR for COVID-19 infections, in mild to moderate stage, among which are 6 males and 8 females with ages ranging from 30 to 77. The two control groups were 13 non-COVID-19 pneumonia patients and 10 healthy people. Then we ...
ORGANISM(S): Homo Sapiens 
2020-07-23 | PXD020522 |
The COVID-19 pandemic has become a world-wide health crisis. So far, most studies have focused on the epidemiology and pathogenesis of this infectious disease. Little attention has been paid to the disease sequelae in patients recovering from COVID-19, and nothing is known about the mechanisms under...
ORGANISM(S): Homo Sapiens 
2020-12-24 | PXD023305 |
Although the landscape of epigenomic and transcriptomic regulation during human pre-implantation development has been depicted by applying single-cell sequencing, the investigation of embryonic proteome is almost unrevealed due to the insufficient input quantity from precious human embryonic samples...
ORGANISM(S): Homo Sapiens 
2021-04-20 | PXD024267 |
We present an integrated analysis of urine and serum proteomics and clinical measurements in asymptomatic, mild/moderate, severe and convalescent cases of COVID-19. We identify the pattern of variation of immune response proteins during COVID-19 infection. The immune response is activated in asympto...
ORGANISM(S): Homo Sapiens 
2021-06-03 | PXD026442 |
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