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ProteomicsLipid mediated–phase separation of AGO proteins on the ER controls nascent peptide ubiquitination
we sought to determine whether dmAGO1 and Ltn1 share common ubiquitinated nascent peptide targets. For this purpose, we performed the UBA bead-based immunoprecipitation followed by mass spec experiments to identify the ubiquitinated nascent peptide targets of dmAGO1 and Ltn1, respectively. In this a...
ORGANISM(S): Drosophila Melanogaster 
2022-02-18 | PXD031749 |
Transcriptomicsp53 and 5hmC in gene regulation
p53 is one of the most frequently mutated genes in human cancers, which could regulate multiple target genes involved in a widespread of cellular processes. The regulation of DNA methylation dynamics is critical for maintaining genome stability and proper gene expression. Recently a family of Ten-El...
ORGANISM(S): Homo sapiens 
2016-04-01 | E-GEOD-53895 | biostudies-arrayexpress
ProteomicsHIRA and dPCIF1 coordinately establish totipotent chromatin and control orderly ZGA in Drosophila embryos
In order to understand the molecular mechanism underlying the action of dPCIF1 in early embryos, we carried out co-immunoprecipitation (co-IP) assays followed by mass spectroscopic analysis using dPCIF1GFP-KI early embryos (0.5–1.5 hours). In this assay, we identified a large number of dPCIF1-intera...
ORGANISM(S): Drosophila Melanogaster 
2024-01-18 | PXD048659 |
UnknownAutomated machine learning-based unenhanced radiomics for identification of HER2-low breast cancers using diffusion-weighted imaging.
Not available
S-EPMC12797709 | biostudies-literature
UnknownPhenotyping of Panicle Number and Shape in Rice Breeding Materials Based on Unmanned Aerial Vehicle Imagery.
Not available
S-EPMC11499587 | biostudies-literature
UnknownIdentification of functional genes regulating gastric cancer progression using integrated bioinformatics analysis.
Not available
S-EPMC10424021 | biostudies-literature
UnknownRevolutionizing Heart Failure Therapy: Harnessing IVT mRNA and Fusion Protein Technology to Prolong rhBNP Half-Life.
Not available
S-EPMC11785693 | biostudies-literature
UnknownThe alteration of intestinal mucosal α-synuclein expression and mucosal microbiota in Parkinson's disease.
Not available
S-EPMC10006030 | biostudies-literature
ProteomicsThe TET-Sall4-BMP regulatory axis controls craniofacial cartilage development
Craniofacial microsomia (CFM) is a congenital defect that usually results from aberrant development of embryonic pharyngeal arches. However, the molecular basis of CFM pathogenesis is largely unknown. Here, we employ the zebrafish model to investigate mechanisms of CFM pathogenesis. In early embryos...
ORGANISM(S): Danio Rerio 
2024-02-02 | PXD049147 |
UnknownA novel superficial temporal artery patency concept of cerebral revascularization for patients with moyamoya disease: a multicenter study.
Not available
S-EPMC12937568 | biostudies-literature
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