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TranscriptomicsRestriction of LINE1 activity by RNAi correlates with mouse ES cell differentiation
Long interspersed elements 1 (LINE-1 or L1) are retrotransposons that dominate the mouse genomic landscape, and are expressed in Embryonic Stem Cells (ESCs), germ cells, and during early development. Based on clear precedents in plants and fission yeast, we investigated in this study a role for RNAi...
ORGANISM(S): Mus musculus 
2013-12-11 | E-GEOD-43110 | biostudies-arrayexpress
UnknownDetection of metastases using circulating tumour DNA in uveal melanoma.
Not available
S-EPMC10602949 | biostudies-literature
UnknownComprehensive analysis of epigenetic clocks reveals associations between disproportionate biological ageing and hippocampal volume.
Not available
S-EPMC9213584 | biostudies-literature
UnknownGenomic analysis reveals that immune function genes are strongly linked to clinical outcome in the North Central Cancer Treatment Group n9831 Adjuvant Trastuzumab Trial.
Not available
S-EPMC4334774 | biostudies-literature
UnknownSequential versus concurrent trastuzumab in adjuvant chemotherapy for breast cancer.
Not available
S-EPMC3236650 | biostudies-literature
UnknownImpact of PTEN protein expression on benefit from adjuvant trastuzumab in early-stage human epidermal growth factor receptor 2-positive breast cancer in the North Central Cancer Treatment Group N9831 trial.
Not available
S-EPMC3731983 | biostudies-literature
UnknownCommon proteomic profiles of induced pluripotent stem cell-derived three-dimensional neurons and brain tissue from Alzheimer patients.
Not available
S-EPMC7457321 | biostudies-literature
TranscriptomicsFactors underlying variable DNA methylation in a human community cohort
Epigenetics is emerging as an attractive mechanism to explain the persistent genomic embedding of early-life experiences. Tightly linked to chromatin, which packages DNA into chromosomes, epigenetic marks primarily serve to regulate the activity of genes. DNA methylation is the most accessible and c...
ORGANISM(S): Homo sapiens 
2012-10-10 | E-GEOD-37008 | biostudies-arrayexpress
UnknownSystematic review protocol of the effectiveness of HIV prevention interventions for reducing risky sexual behaviour among youth globally.
Not available
S-EPMC9109094 | biostudies-literature
TranscriptomicsThe developmental dynamics and disease potential of random monoallelic gene expression
X-chromosome inactivation (XCI) in females and allelic exclusion of olfactory receptor or immunoglobulin loci, represent classic examples of random monoallelic expression (RME). RME of some single copy genes has also been reported, but the in vivo relevance of this remains unclear. Here we identify ...
ORGANISM(S): Mus musculus 
2014-02-27 | E-GEOD-54016 | biostudies-arrayexpress
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