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ProteomicsMCT1-governed pyruvate metabolism is essential for antibody class-switch recombination through H3K27 acetylation
Monocarboxylate transporter 1 (MCT1) exhibits essential roles in cellular metabolism and energy supply. Although MCT1 is highly expressed in activated B cells, it is not clear how MCT1-governed monocarboxylates transportation is functionally coupled to antibody production during the glucose metaboli...
ORGANISM(S): Mus musculus (Mouse) 
2023-12-14 | PXD047325 | Pride
B cell Lc-ms/ms A20 Nuclei 
ProteomicsSlc44a2 deficiency unveils an IFN-I–dependent feedback control of pDC egress
This project aims to characterize the proteomic landscape of bone marrow-derived plasmacytoid dendritic cells (pDCs) from wild-type (WT) and Slc44a2-deficient (cKO) mice.
ORGANISM(S): Mus Musculus 
2026-03-31 | PXD076360 |
UnknownAbrupt Transition of Nanothermite Reactivity: The Roles of Loading Density, Microstructure and Ingredients.
Not available
S-EPMC12565809 | biostudies-literature
UnknownPembrolizumab promotes degradation of cyclin dependent kinase 6 and suppresses ovarian cancer progression in vitro.
Not available
S-EPMC12255764 | biostudies-literature
ProteomicsSLC6A6 imports taurine into mitochondria to sustain mitochondrial translation and tumour growth
Taurine plays a crucial role in mitochondrial tRNA modification essential for mitochondrial translation. Mammalian cells obtain taurine through plasma membrane transporter SLC6A6-mediated uptake exogenously or cytosolic biosynthesis. However, it remains unclear how taurine enters mitochondria and im...
ORGANISM(S): Homo Sapiens 
2025-11-29 | PXD071408 |
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