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ProteomicsCombined transcriptome and proteome profiling for role of pfEMP1 in antimalarial mechanism of action of dihydroartemisin
Malaria parasites induce morphological and biochemical changes in the membranes of parasite-infected red blood cells (iRBCs) for propagation. Artemisinin combination therapies are the first-line antiplasmodials in endemic countries. However, the mechanism of action of artemisinin is unclear, and dru...
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2022-02-15 | PXD028062 | Pride
Mode of action Irbc membrane proteome Dihydroartemisin Malaria 
TranscriptomicsTranscriptomic Assay of CD8 2012-05-15
In this study, Genome-wide transcriptomes of CD8+ T cells from HCV/HIV co-infected or mono-infected treatment-naive individuals were analyzed by using microarray assays. Pairwise comparisons were performed and differentially expressed genes were identified followed by quantitative real time PCR (qRT...
ORGANISM(S): Homo sapiens 
2012-05-17 | E-MEXP-3635 | biostudies-arrayexpress
TranscriptomicsNA-Seq reveals dynamic changes of gene expression in key stages of intestine regeneration in the sea cucumber Apostichopus japonicus.
Sea cucumbers (Holothuroidea; Echinodermata) have the capacity to regenerate lost tissues and organs.We used RNA-Seq to determine gene expression profiles associated with intestinal regeneration in A. japonicus at 3, 7, 14 and 21 days post evisceration (dpe) At least 15 individuals per stage, at 3,...
ORGANISM(S): Apostichopus japonicus 
2015-01-01 | E-GEOD-44995 | biostudies-arrayexpress
UnknownBis[μ-N-(tert-butyl-dimethyl-sil-yl)quinolin-8-aminato-1:2κ(2) N (1),N (8):N (8)](N,N,N',N'-tetra-methyl-ethane-1,2-diamine-1κ(2) N,N')lithiumsodium.
Not available
S-EPMC3588735 | biostudies-literature
UnknownPredictive markers for early conversion of iRBD to neurodegenerative synucleinopathy diseases.
Not available
S-EPMC5395071 | biostudies-literature
TranscriptomicsTranscription profiling of human clear cell renal cell carcinoma cell lines
Systematic somatic mutation screening in human clear cell renal cell carcinoma reveals inactivation of chromatin modification genes
ORGANISM(S): Homo sapiens 
2009-10-01 | E-TABM-770 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human cancers with inactivating somatic mutations of the histone H3K27 demethylase UTX
We describe inactivating somatic mutations in the histone lysine demethylase, UTX, in human cancers pointing to the deregulation of histone H3 lysine methylation in the development of multiple tumour types. Gene expression was analysed on Illumina Human WG-6 v2 BeadChips following standard protocols...
ORGANISM(S): Homo sapiens 
2009-02-16 | E-MTAB-84 | biostudies-arrayexpress
UnknownInborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children.
Not available
S-EPMC10451000 | biostudies-literature
GenomicsChIP-seq of ERG-bound regulatory elements in human and bovine vascular endothelial cells
In this study we set out to discover conserved orthologous ERG-bound gene regulatory elements in primary vascular endothelial cells isolated from human and cow
ORGANISM(S): Homo sapiens 
2017-06-15 | E-MTAB-5148 | biostudies-arrayexpress
TranscriptomicsApplied Biosystems Human TaqMan Low Density Array (TLDA) in plasma samples from EOC cases and controls
Most (70%) epithelial ovarian cancers (EOCs) are diagnosed late. Non-invasive biomarkers that facilitate disease detection and predict outcome are needed. The microRNAs (miRNAs) represent a new class of biomarkers. This study was to identify and validate plasma miRNAs as biomarkers in EOC. We evalua...
ORGANISM(S): Homo sapiens 
2013-08-30 | E-GEOD-50472 | biostudies-arrayexpress
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