Sort   by:  
 Page size 
ProteomicsCombined transcriptome and proteome profiling for role of pfEMP1 in antimalarial mechanism of action of dihydroartemisin
Malaria parasites induce morphological and biochemical changes in the membranes of parasite-infected red blood cells (iRBCs) for propagation. Artemisinin combination therapies are the first-line antiplasmodials in endemic countries. However, the mechanism of action of artemisinin is unclear, and dru...
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2022-02-15 | PXD028062 | Pride
Mode of action Irbc membrane proteome Dihydroartemisin Malaria 
UnknownDesign, synthesis, and biological evaluation of artemisinin-indoloquinoline hybrids as potent antiproliferative agents.
Not available
S-EPMC6271626 | biostudies-literature
TranscriptomicsExpression data from DU145 prostate cancer cells treated with DHA or DMSO
Axl expression is deregulated in several cancer types, predicts poor overall patient survival and is linked to increase in resistance to drug therapy. Here, we have evaluated a library of natural compounds for inhibitors of Axl. We identified dihydroartemisin (DHA), the active principle of the anti-...
ORGANISM(S): Homo sapiens 
2018-11-17 | GSE122625 | GEO
UnknownProbucol-Induced α-Tocopherol Deficiency Protects Mice against Malaria Infection.
Not available
S-EPMC4546625 | biostudies-literature
GenomicsAntimalarial genetic screens of Plasmodium falciparum show peculiarities between the DHA and BTZ responses
Antimalarial genetic screens of Plasmodium falciparum show peculiarities between the DHA and BTZ responses
PRJNA779388 | ENA
Genomics
transcriptomic of plasmodium parasite after dihydroartemisinin treatment
PRJNA756448 | ENA
UnknownRandomized trial of piperaquine with sulfadoxine-pyrimethamine or dihydroartemisinin for malaria intermittent preventive treatment in children.
Not available
S-EPMC2747010 | biostudies-literature
UnknownSingle dose primaquine to reduce gametocyte carriage and Plasmodium falciparum transmission in Cambodia: An open-label randomized trial.
Not available
S-EPMC5462369 | biostudies-literature
UnknownEffectiveness and safety of reactive focal mass drug administration (rfMDA) using dihydroartemisinin-piperaquine to reduce malaria transmission in the very low-endemic setting of Eswatini: a pragmatic cluster randomised controlled trial.
Not available
S-EPMC8246301 | biostudies-literature
UnknownMixed-method evaluation study of a targeted mass drug administration of long-acting anti-malarials among children aged 3 months to 15 years in the Bossangoa sub-prefecture, Ouham, Central African Republic, during the COVID-19 pandemic.
Not available
S-EPMC11094902 | biostudies-literature
Sort   by:  
 Page size