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We used immunoprecipitation to pulldown Lin28 associated RNA targets and used genome-wide high throughput deep sequencing to identified those Lin28-associated RNAs. Keywords: Lin28 IP-RNAseq Examination of Lin28 immunoprecipitated RNA transcripts
ORGANISM(S): Homo sapiens 
We describe the discovery of sno-lncRNAs, a class of nuclear-enriched intron-derived long noncoding RNAs (lncRNAs) that are processed on both ends by the snoRNA machinery. During exonucleolytic trimming, the sequences between the snoRNAs are not degraded, leading to the accumulation of lncRNAs flank...
ORGANISM(S): Homo sapiens 
We have used deep sequencing to explore the repertoire of both poly(A)+ and poly(A)- RNAs from two standard cell lines, HeLa cells and human embryonic stem cell (hESC) H9 cells. Examination of nonpolyadenylated and polyadenylated in 2 cell types.
ORGANISM(S): Homo sapiens 
We have used RNA-seq to examine gene expression from paired human CRC/control mucosa samples and identified CRC-specific expressed long noncoding RNAs To identify CRC-specific expressed genes, including long noncoding RNAs
ORGANISM(S): Homo sapiens 
CCAT1-L is a highly expressed long noncoding RNA located in the colorectal cancer specific super enhance region about 500 kb upstream of MYC gene. Knockdown of CCAT1-L significantly down-regulated interaction frequency between CCAT1 and MYC locus and repress MYC expression, suggesting a long-range c...
ORGANISM(S): Homo sapiens 
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