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TranscriptomicsRNA-seq of primary human fetal RPE cells (hfRPE) treated with IL1α, with and without prior high-dose zinc supplementation, compared to untreated controls
A RPE cell model mimicking a mature RPE was used to investigate the potential anti-inflammatory effects of high-dose zinc supplementation in the context of AMD research. RPE cultures were exposed to inflammatory conditions induced by interleukin 1α (IL-1α) after a 14-day treatment with high doses of...
ORGANISM(S): Homo sapiens 
2025-08-14 | E-MTAB-15373 | biostudies-arrayexpress
TranscriptomicsRNA-seq of primary human fetal RPE cells (hfRPE) treated with IL1α with and without Zn supplementation against untreated controls
A RPE cell model mimicking a matured RPE was subjected to an acute inflammatory stress with and without Zn supplementation and the effects of such exposure were evaluated by studying alterations at the transcriptome level. The experiment performed aim to improve the understanding of the metabolic pr...
ORGANISM(S): Homo sapiens 
2022-07-08 | E-MTAB-11891 | biostudies-arrayexpress
UnknownDupilumab provides favourable long-term safety and efficacy in children aged ≥ 6 to < 12 years with uncontrolled severe atopic dermatitis: results from an open-label phase IIa study and subsequent phase III open-label extension study.
Not available
S-EPMC8247037 | biostudies-literature
TranscriptomicsTranscriptional Analysis of Deinococcus radiodurans for Novel sRNAs expression that are Differentially Expressed under Ionizing Radiation
In this study, we identified potential sRNA candidates in D. radiodurans by a whole transcriptome deep sequencing analysis, and confirm the expression of 31 sRNAs in D. radiodurans with Northern blotting analysis and RT-PCR. A total of 8 confirmed sRNAs showed differential expression during recover...
ORGANISM(S): Deinococcus radiodurans R1 
2015-01-22 | E-GEOD-64952 | biostudies-arrayexpress
TranscriptomicsA histone H3K36 chromatin switch coordinates DNA double-strand break repair pathway choice.
Wildtype and set2delta strains, with samples taken at t=0 and following 30 minutes treatment with 5 µg/ml bleomycin.
ORGANISM(S): Schizosaccharomyces pombe 
2014-06-09 | E-MTAB-2549 | biostudies-arrayexpress
UnknownDupilumab Treatment Leads to Rapid and Consistent Improvement of Atopic Dermatitis in All Anatomical Regions in Patients Aged 6 Months to 5 Years.
Not available
S-EPMC10442292 | biostudies-literature
UnknownSalivary microbiome in chronic kidney disease: what is its connection to diabetes, hypertension, and immunity?
Not available
S-EPMC9441058 | biostudies-literature
UnknownDissecting structure-function of 3-O-sulfated heparin and engineered heparan sulfates.
Not available
S-EPMC8694587 | biostudies-literature
UnknownAirway Mucus Hyperconcentration in Non-Cystic Fibrosis Bronchiectasis.
Not available
S-EPMC7068838 | biostudies-literature
UnknownEvaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries.
Not available
S-EPMC10771257 | biostudies-literature
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