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MetabolomicsM3-Driven Hexosamine Biosynthesis Facilitates Hepatocellular Carcinoma Progression through YBX1 O-GlcNAcylation
Phosphoglucomutase 3 (PGM3) is one of the rate-limiting enzymes in the hexosamine biosynthesis pathway (HBP) and a key regulator of HBP metabolic flux. Despite the functional role of PGM3 has been validated in various tumors, its function and molecular mechanism in hepatocellular carcinoma (HCC) rem...
2026-09-04 | MTBLS15552 | MetaboLights
TranscriptomicsHigh salt primes a specific activation state of macrophages, M(Na)
Purpose: Investigate effects of high salt on human macrophage activation Methods: Human monocytes-derived macrophages were treated by additional 51mM NaCl for 24 hours (NaCl groups) or not (Control groups). mRNA profiles were generated by RNA-Seq, in triplicate, using Ion proton（Life tech). qRT–PCR ...
ORGANISM(S): Homo sapiens 
2015-09-23 | E-GEOD-68482 | biostudies-arrayexpress
ProteomicsIdentification of cellular proteins interacting with PEDV M protein through APEX2 labeling
Membrane (M) proteins of coronaviruses are the most abundant component of the virus envelope and play crucial roles in virus assembly, virus budding and the regulation of host immunity. To understand more about these functions in the context of PEDV M protein, forty host cell proteins interacting wi...
ORGANISM(S): Sus Scrofa Scrofa 
2021-03-07 | PXD024559 |
TranscriptomicsTranscriptional profiling of ATCC46645 strain and isogenic M-NM-^TpacC Aspergillus fumigatus mutant during murine infection
In lung diseases caused by the major mould pathogen Aspergillus fumigatus the pulmonary epithelium is destroyed by invasive growth of fungal hyphae, a process thought to require fungal proteases. Here we show that the A. fumigatus pH-responsive transcription factor PacC governs expression of secrete...
ORGANISM(S): Aspergillus fumigatus 
2014-10-20 | E-GEOD-54810 | biostudies-arrayexpress
TranscriptomicsMFAP4 is an integrin M-NM-1VM-NM-23/5 ligand involved in vascular remodeling
Arterial injury or occlusive arterial disease may stimulate healing responses, which when overexuberant, leads to restenosis of the injured vessel. This response is influenced by specific integrin signalling in vascular smooth muscle cells (VSMCs). Microfibril-associated protein 4 (MFAP4) colocates ...
ORGANISM(S): Mus musculus 
2013-04-01 | E-GEOD-40480 | biostudies-arrayexpress
TranscriptomicsThe Fun30 ATP-dependent nucleosome remodeler promotes resection of DNA double-strand break ends
Chromosomal double-strand breaks (DSBs) are resected by 5M-bM-^@M-^Y-nucleases to form 3M-bM-^@M-^Y single-strand DNA (ssDNA) substrates for binding by homologous recombination and DNA damage checkpoint proteins. Two redundant pathways of extensive resection were described both in cells and in vitro...
ORGANISM(S): Saccharomyces cerevisiae 
2012-10-04 | E-GEOD-38601 | biostudies-arrayexpress
TranscriptomicsExpression data of Actinobacillus pleuropneumoniae 4074, the M-NM-^TluxS mutant and AI-2 supplemented M-NM-^TluxS mutant
LuxS is an enzyme involved in the activated methyl cycle. The by-product of this cycle, autoinducer 2 (AI-2), could be an important quorum sensing signal. LuxS was conserved and regulated many behaviors in different bacteria, but in most species, whether the regulations are related to AI-2 mediated ...
ORGANISM(S): Actinobacillus pleuropneumoniae 
2011-11-15 | E-GEOD-21300 | biostudies-arrayexpress
TranscriptomicsExpression data of Actinobacillus pleuropneumoniae 4074 and the M-NM-^TluxS mutant of Actinobacillus pleuropneumoniae 4074
LuxS is an enzyme involved in the activated methyl cycle and the by-product autoinducer 2 (AI-2) was a quorum sensing signal in some species. In our previous study, the functional LuxS in AI-2 production was verified in the porcine respiratory pathogen Actinobacillus pleuropneumoniae. Enhanced biofi...
ORGANISM(S): Actinobacillus pleuropneumoniae 
2011-11-09 | E-GEOD-19056 | biostudies-arrayexpress
UnknownThe Role of m6A/m-RNA Methylation in Stress Response Regulation.
Not available
S-EPMC6069762 | biostudies-literature
UnknownM(salen)-derived nitrogen-doped M/C (M = Fe, Co, Ni) porous nanocomposites for electrocatalytic oxygen reduction.
Not available
S-EPMC4034751 | biostudies-literature
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