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The sea cucumber Apostichopus japonicus withstands high water temperatures in the summer by suppressing metabolic rate and entering a state of aestivation. We hypothesized that changes in the expression of miRNAs could provide important post-transcriptional regulation of gene expression during hypom...
ORGANISM(S): Apostichopus japonicus 
The regulatory role of miRNA in gene expression is an emerging hot new topic in the control of hypometabolism. Sea cucumber aestivation is a complicated physiological process that includes obvious hypometabolism as evidenced by a decrease in the rates of oxygen consumption and ammonia nitrogen excre...
ORGANISM(S): Apostichopus japonicus 
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Apostichopus japonicus 
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Apostichopus japonicus 
The objective of this study was to perform a detailed analysis of neuropeptides in A. japonicus by sequencing the transcriptome of neural tissue (circumoral nerve ring; CNR) and combining analysis of these sequence data with mass spectroscopic analysis of CNR extracts so that the structure of mature...
ORGANISM(S): Stichopus japonicus (Sea cucumber) 
2019-06-25 | PXD013818 | Pride
Sea cucumbers (Holothuroidea; Echinodermata), cycle annually between aestivation when water temperature is above about 25°C in the summer and active life when temperature is below about 18°C. We used RNA-Seq to determine gene expression profiles of intestine tissue of A.japonicus during non-aestivat...
ORGANISM(S): Apostichopus japonicus 
Sea cucumbers (Holothuroidea; Echinodermata) cycle annually between aestivation, when water temperature is above about 25°C in the summer, and active life, when temperature is below about 18°C. We used RNA-Seq to determine gene expression profiles of respiratory tree tissue of A. japonicus during ...
ORGANISM(S): Apostichopus japonicus 
Oxaliplatin-based therapeutics is a widely used treatment approach for hepatocellular carcinoma (HCC) patients; however, drug resistance poses a significant clinical challenge. Epigenetic modifications have been implicated in the development of drug resistance. In our study, employing siRNA library ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD044817 | Pride
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