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All the reports on insect small RNAs come from holometabolous insects. However, small RNAs of hemimetabolous insects have not yet been investigated.Study of hemimetabolous insect small RNAs could provide more insights into evolution and function of small RNAs in hemi- and holometabolous insects. The...
ORGANISM(S): Locusta migratoria 
The phytohormone abscisic acid (ABA) regulates plant responses to environmental stresses, development, and immunity. Under unfavorable conditions, ABA forms a complex with its receptor proteins PYR1/PYLs/RCARs, inhibiting A clade PP2C phosphatases and releasing SnRK2s from PP2C-mediated inhibition. ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-11-10 | PXD053394 | Pride
The prognosis of colorectal cancer (CRC) stage II and III patients is still a challenge due to the difficulties of finding robust biomarkers and assays. The majority of published gene signatures of CRC have been generated on frozen colorectal tissues. Because collection of fresh frozen tissues is no...
ORGANISM(S): Homo sapiens 
Arsenic is a carcinogen that is known to induce cell transformation and tumor formation. Although studies have been performed to examine the modulation of signaling molecules caused by arsenic exposure, the molecular mechanisms by which arsenic causes cancer are still unclear. We hypothesized that ...
ORGANISM(S): Rattus norvegicus 
The rapid activation of RAF-SnRK2 cascades in response to hyperosmolarity is a crucial event in plants' adaptation to osmotic stress, yet the underlying mechanisms have remained elusive. In this study, we reveal that the calcium chelator EGTA, but not other calcium modulators, can potently activate ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2024-04-18 | PXD046802 | Pride
Phosphorylation-mediated signaling transduction plays a crucial role in the regulation of plant defense mechanisms against environmental stresses. To address the high complexity and dynamic range of plant proteomes and phosphoproteomes, we present a universal sample preparation procedure that facili...
ORGANISM(S): Solanum Pimpinellifolium Solanum Lycopersicum 
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