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UnknownPhase IIb trial of in vivo electroporation mediated dual-plasmid hepatitis B virus DNA vaccine in chronic hepatitis B patients under lamivudine therapy.
Not available
S-EPMC5236510 | biostudies-literature
GenomicsTET2 KD and ChIP-Seq
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2012-12-11 | E-GEOD-41722 | biostudies-arrayexpress
UnknownHost-inducible immunogenic sphingomyelinase-like protein, Lk73.5, of Leptospira interrogans.
Not available
S-EPMC321616 | biostudies-literature
GenomicsOGT, H2B S112GlcNAc, TET2 ChIP-seq results
TET2 directly interacts with OGT, which is important for the chromatin association of OGT in vivo. Although this specific interaction does not regulate the enzymatic activity of TET2, it facilitates OGT-dependent histone O-GlcNAcylation. Moreover, OGT associates with TET2 at transcription starting s...
ORGANISM(S): Mus musculus 
2012-12-11 | E-GEOD-41720 | biostudies-arrayexpress
ProteomicsMulti-omics profiling reveals systemic rejuvenation of the aged kidney through senolytic therapy
Cellular senescence is a key driver of kidney aging, leading to functional decline and increased susceptibility to chronic kidney disease. While the senolytic combination of dasatinib and quercetin (D+Q) has shown promise in mitigating age-related pathologies, its long-term effects and underlying mu...
ORGANISM(S): Homo Sapiens 
2026-03-24 | PXD076057 |
TranscriptomicsExpression data from ES cells
TET2 directly interacts with OGT, which is important for the chromatin association of OGT in vivo. Although this specific interaction does not regulate the enzymatic activity of TET2, it facilitates OGT-dependent histone O-GlcNAcylation. Moreover, OGT associates with TET2 at transcription starting s...
ORGANISM(S): Mus musculus 
2012-12-11 | E-GEOD-41721 | biostudies-arrayexpress
ProteomicsLoss of Cep70 function affects acrosome biogenesis and flagella formation during spermiogenesis
The spermatogenesis process is complex and delicate, and any error in any step may cause spermatogenesis arrested and even male infertility. Through mutation screening of patients with clinical azoospermia, we found a heterozygous site of the same mutation on CEP70. The centrosome protein 70 (Cep70)...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-10 | PXD023680 | Pride
Cep70  male infertility  acrosome biogenesis  flagella formation  spermiogenesis 
ProteomicsPhosphoproteomic sequencing of Glycine max under alkali stress
Alkali stress is one of the most severe abiotic stresses affecting agricultural production worldwide. To understand the phosphorylation events in soybean in response to alkali stress, we performed the TMT labeling-based quantitative phosphoproteomic analyses on soybean leaf and root tissues under 50...
ORGANISM(S): Glycine max 
2024-01-26 | PXD041842 | Pride
Alkali stress Soybean Phosphoproteomics 
ProteomicsOryza sativa extracellular vesicles proteins
Cross-kingdom molecular exchange between hosts and interacting microbes is essential for the survival of both plants and their pathogens. Recent studies showed plants transfer their small RNAs (sRNAs) and massager RNAs (mRNAs) into fungal pathogens to suppress infection. However, whether and how pla...
ORGANISM(S): Oryza sativa (Rice) 
2025-01-06 | PXD048458 | Pride
Extracellular vesicles Plants interacting with pathogens 
ProteomicsEndothelial ether lipids link blood vessels to neurodegeneration
Vascular disease contributes to neurodegeneration, which is associated with decreased blood pressure in older humans. Plasmalogens, ether phospholipids produced by peroxisomes, are decreased in Alzheimer’s disease, Parkinson’s disease and other neurodegenerative disorders. Here we show that endothel...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-10 | PXD024116 | Pride
Mouse Q-exactive Phospholipids/biosynthesis Glycerophospholipids Vascular biology/endothelial cells Plasmalogens Peroxisomes 
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