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ProteomicsDeciphering functions of VHL in Clear Cell Renal Cell Carcinoma
VHL is the most frequently mutated gene in ccRCC.It functions via the oxygen-dependent ubiquitin-mediated degradation of hypoxia-inducible factor (HIF). The stabilization and hyperactivation of HIF1 play essential roles in tumorigenesis. This is a TMT based proteomics experiment aimed to investigate...
ORGANISM(S): Homo sapiens (Human) 
2023-01-05 | PXD012665 | Pride
Renal cancer  vhl  immunogenicity  proteostasis 
ProteomicsIgA Nephropathy Proteome Profiling
IgA nephropathy (IgAN) is a heterogeneous disease, which poses a series of challenges to accurate diagnosis and personalized therapy. Here, we present a systematic quantitative kidney tissue proteome atlas across 19 tumor-adjacent normal kidney tissues, 12 membranous nephropathy (MN) samples and 59 ...
ORGANISM(S): Homo Sapiens 
2022-03-22 | PXD032710 |
ProteomicsBacterial proteins of Yersinia pestis mutant ΔyscI
Y. pestis strain 201 and mutant ΔyscI cultures grown under Mh (37°C, TMH with no calcium) condition were used as the experimental and control groups, respectively. After 8 h of incubation, the bacterial pellets were collected by centfugation, re-suspended in lysis buffer (8 M urea in PBS, pH 7.4) an...
ORGANISM(S): Yersinia Pestis Co92 
2020-12-16 | PXD023156 |
ProteomicsProteome of Yersinia pestis 201 at 26℃ mimic flea
The secreted proteome and bacteria proteome of yersinia pestis at 26 ℃ mimic flea. Y. pestis strain 201 cultures grown under Fv (26°C, TMH with 2.5M calcium) condition. The bacteria pellets and supernant were used as the experimental and control groups, respectively. After 8 h of incubation, the cul...
ORGANISM(S): Yersinia Pestis Co92 
2020-12-16 | PXD023157 |
ProteomicsProteome of Yersinia pestis 201 at 37℃ mimic human
The secreted proteome and bacteria proteome of yersinia pestis at 37℃ mimic human. Y. pestis strain 201 cultures grown under Mh (37°C, TMH with no calcium) condition were used as the experimental and control groups, respectively. After 8 h of incubation, the cultures supernatants were collected by c...
ORGANISM(S): Yersinia Pestis Co92 
2020-12-16 | PXD023183 |
ProteomicsParallel reaction monitoring analysis of target proteins
Parallel reaction monitoring (PRM) analysis was used to confirm changes in abundance of the target proteins (AceF, SodA, YopD, YopE, GroEL, TerE, and OsmY2),. Equal amounts of proteins from the culture supernatants and cell pellets were separated by SDS-PAGE, and bands corresponding to each of the t...
ORGANISM(S): Yersinia Pestis Co92 
2020-12-16 | PXD020061 |
ProteomicsBacterial proteins of Yersinia pestis 201
Y. pestis strain 201 cultures grown under Mh (37°C, TMH with no calcium) and Fv (26°C, TMH with 2.5M calcium) conditions were used as the experimental and control groups, respectively. After 8 h of incubation, the bacterial pellets were collected by centfugation, re-suspended in lysis buffer (8 M ur...
ORGANISM(S): Yersinia Pestis Co92 
2020-12-16 | PXD020063 |
ProteomicsSecreted proteins of Yersinia pestis 201
Y. pestis strain 201 cultures grown under Mh (37°C, TMH with no calcium) and Fv (26°C, TMH with 2.5M calcium) conditions were used as the experimental and control groups, respectively. After 8 h of incubation, the cultures supernatants were collected by centfugation and concentrated using centrifuga...
ORGANISM(S): Yersinia Pestis Co92 
2020-12-16 | PXD020062 |
ProteomicsSecreted proteins of Yersinia pestis mutant ΔyscI
Y. pestis strain 201 and mutant ΔyscI cultures grown under Mh (37°C, TMH with no calcium) condition were used as the experimental and control groups, respectively. After 8 h of incubation, the cultures supernatants were collected by centfugation and concentrated using centrifugal filters. The concen...
ORGANISM(S): Yersinia Pestis Co92 
2020-12-16 | PXD020060 |
ProteomicsTargets identification of Danhong injection by iTSA
Proteomics data of targets identification of Danhong injection(10plex TMT)
ORGANISM(S): Homo Sapiens 
PXD052842 |
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