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TranscriptomicsThe Global Transcriptional Response of Fission Yeast to Hydrogen Sulfide
Hydrogen sulfide (H2S) as an important gasotransmitter has fundamental roles in human diseases. The cellular effect of H2S has received lots of attention recently. H2S can affect ion channels, transcription factors and kinase in mammals. The mechanism of cellular effect of H2S is not completely unde...
ORGANISM(S): Schizosaccharomyces pombe 
2012-06-14 | E-GEOD-30025 | biostudies-arrayexpress
ProteomicsDisclosing potential therapeutic targets associated with Osimertinib resistance in non-small cell lung cancer cell line H1975
H1975/OSI cell line was induced in vitro through intermittent induction. Cell activity was measured using cell counting kit-8 assay. Uni-omics and multi-omics analyses were conducted on the transcriptomic and proteomic (4D label-free) expression profiles, which involved differential expression analy...
ORGANISM(S): Homo Sapiens 
2023-07-18 | PXD043855 |
ProteomicsAI-facilitated multi-omics reveal TRF-controlled propionylation in determining protein homeostasis
Firstly, we systematically identified rhythmically modified Kpr sites, through time-series propionylomic profiling of fly heads. Wild-type (WT) and per0 flies were entrained under light/dark cycles (LD) and then released into constant darkness (DD), respectively. On the first day of DD, whole heads ...
ORGANISM(S): Drosophila Melanogaster 
2023-03-20 | PXD040987 |
ProteomicsTranscriptomic and proteomic analysis reveals a core Atg9 interactome in the regulation of yeast macroautophagy
In Saccharomyces cerevisiae, Atg9 is an important AuTophaGy-related (Atg) protein, plays critical roles in regulating macroautophagy/autophagy, and physically interacts with hundreds of proteins. How Atg9 interacting partners are synergistically orchestrated in autophagy are unclear. Here, we conduc...
ORGANISM(S): Saccharomyces Cerevisiae 
2019-01-19 | PXD012458 |
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