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ProteomicsProteogenomic landscape of the Esophageal Squamous Cell Cancer reveals the lipid droplet formation process as a novel therapeutic target
The integrated proteogenomic analysis revealed proteomic characteristics associated with genomic variants and clinical features including arm or focal amplifications, SNV mutations, tumor size, lymph node metastasis, smoking history.
ORGANISM(S): Homo Sapiens 
2025-03-24 | PXD062163 |
ProteomicsResveratrol against Aeromonas hydrophila through proteomics analysis
Resveratrol against Aeromonas hydrophila through proteomics analysis on an Q Exactive HF mass spectrometer (Thermo Scientific, United States) .
ORGANISM(S): Aeromonas Hydrophila Subsp. Hydrophila Atcc 7966 
2024-01-29 | PXD048957 |
ProteomicsCalcium-mediated calreticulin IRE1α interaction drives dynamic fluctuation of IRE1α activity under chronic endoplasmic reticulum stress
To investigate the mechanisms underlying fluctuating IRE1α phosphorylation under chronic endoplasmic reticulum stress, we performed co-immunoprecipitation coupled with mass spectrometry (IP-MS) to identify IRE1α-interacting proteins. Protein complexes were analyzed by LC-MS/MS, followed by bioinform...
ORGANISM(S): Homo Sapiens 
2026-01-30 | PXD073899 |
ProteomicsOLFM4 is a direct target of the cGAS-STING pathway and acts as an extracellular inhibitor for the Hippo signaling in EBV-associated cancer
To investigate protein components of MVs in EBVaGC, we collected clinical tissue samples of 3 EBV+ and 3 EBV- gastric cancer patients, and isolated MVs from these samples. Then performed 4D-label free quantitative proteomics analysis for each isolated MVs. Raw files of 6 samples are included in subp...
ORGANISM(S): Homo Sapiens 
2024-11-18 | PXD057977 |
ProteomicsLarge-scale Proteome Profiling Identifies Biomarkers Associated with Suspected Neurosyphilis Diagnosis
Neurosyphilis (NS) is a central nervous system infection caused by Treponema pallidum. NS can occur at any stage of syphilis and manifests as a broad spectrum of clinical symptoms. Often referred to as “the great imitator”, NS can be easily overlooked or misdiagnosed due to the absence of standard d...
ORGANISM(S): Homo Sapiens 
2024-02-16 | PXD033034 |
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