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TranscriptomicsExpression analysis of superior cervical ganglion from backcrossed TH-MYCN transgenic mice
Neuroblastoma susceptibility in TH-MYN mice is heavily influence by mouse strain background. We have combined linkage analysis of tumor susceptibility with expression QTL analysis of superior cervical ganglia (pure peripheral symptathetic nervous tissue) to identify genes underlying tumor formation...
ORGANISM(S): Mus musculus 
2015-01-30 | E-GEOD-59675 | biostudies-arrayexpress
UnknownGene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations.
Not available
S-EPMC3988452 | biostudies-literature
TranscriptomicsThe effect of short term Rapamycin on the transcriptome of old mouse liver
Analysis of the effect of gene expression in the livers of old mice (25 months of age) fed rapamycin short term (6 months) Rapamycin from 19 months of age. Total RNA extracted from livers of 25 month old C57BL6/N male and female mice started on control or 14 ppm rapamycin (Rapa) from 19 months of ag...
ORGANISM(S): Mus musculus 
2014-02-07 | E-GEOD-48331 | biostudies-arrayexpress
TranscriptomicsThe effect of chronic Rapamycin on the transcriptome of old mouse liver
Analysis of the effect of gene expression in the livers of old mice (25 months of age) fed rapamycin chronically (21 months) from 4 months of age. Total RNA extracted from livers of 25 month old C57BL6/J male and female mice started on control or 14 ppm rapamycin (Rapa) from 4 months of age on 21 mo...
ORGANISM(S): Mus musculus 
2014-02-07 | E-GEOD-48333 | biostudies-arrayexpress
TranscriptomicsThe effect of Rapamycin on the transcriptome of old mouse liver
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2014-02-07 | E-GEOD-48334 | biostudies-arrayexpress
TranscriptomicsThe genetics of splicing in neuroblastoma
Regulation of mRNA splicing is a critical and tightly regulated cellular function, underlying the majority of proteomic diversity in our genomes. While disruption of this process is common in disease, the basic genetic complexity of alternative splicing in vivo remains poorly understood. To delinea...
ORGANISM(S): Mus musculus 
2015-04-03 | E-GEOD-55248 | biostudies-arrayexpress
ProteomicsVestibular schwannoma is comprised of neural crest and immune subgroups
Vestibular schwannomas (VS) are tumors arising from cranial nerve Schwann cells that cause significant morbidity and are treated with surgery and irradiation. We describe a DNA methylation-based classification of VS into neural crest and immune enriched subgroups and validate our findings using bulk...
ORGANISM(S): Homo Sapiens 
PXD014883 | panorama
UnknownCold and heterogeneous T cell repertoire is associated with copy number aberrations and loss of immune genes in small-cell lung cancer.
Not available
S-EPMC8599854 | biostudies-literature
UnknownDisease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium.
Not available
S-EPMC5546242 | biostudies-literature
UnknownStructural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Not available
S-EPMC4683157 | biostudies-literature
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