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Blocking the PD-1/PD-L1 immunosuppressive pathway has shown promise in the treatment of certain cancers including melanoma. This study investigates differences in the gene expression profiles of human melanomas that do or do not display the immunosuppressive protein PD-L1. Further understanding of g...
ORGANISM(S): Homo sapiens 

Background

Cannabis sativa, a dioecious plant that has been cultivated worldwide for thousands of years, is known for its secondary metabolites, especially cannabinoids, which possess several medicinal effects. In this study, we investigated the autopolyploidization effects on the biosynthes...
2023-09-21 | MTBLS6032 | MetaboLights
Hypoxia represents a major physiological challenge for prawns and is a problem in aquaculture. Therefore, an understanding of the metabolic response mechanism of economically important prawn species to hypoxia and re-oxygenation is essential. However, little is known about the intrinsic mechanisms b...
2021-05-17 | MTBLS584 | MetaboLights
Here we present MS data of ERα-NTD protein samples exposed to 0-50 ms of X-ray beam at the Advanced Light Source (Berkeley, CA). Irradiated protein samples were digested with two sets of proteases, Asp-N and Lys-C, and pepsin. LC-MS/MS data was utilized to identify 16 sites of modification listed in...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD011361 | Pride

BACKGROUND: Diet is foods and drinks regularly consumed, and its regulation is complicated. It is necessary to obtain a practical understanding of which foods and drinks contribute to health and well-being and which are insalubrious. Clear evidence shows that a high intake of fru...

2022-08-24 | MTBLS4108 | MetaboLights
Pseudomonas aeruginosa, X-ray irradiation, inner membrane blebbing, membrane vesicles Almost all bacteria produce membrane vesicles (MVs) that have been found to be generally composed of lipopolysaccharides (LPSs), phospholipids (PLs), outer membrane proteins, periplasmic proteins and peptidoglycan ...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2025-08-25 | PXD037062 | Pride
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