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MetabolomicsMetabolite signatures of diverse Camellia sinensis tea populations
Tea plants (Camellia sinensis) present an excellent system to study evolution and diversification of specialized metabolites due to their abundance in classes, numbers and contents. A large number of tea cultivars have been cultivated throughout the world not only because of their adaption to differ...
2020-10-05 | MTBLS1405 | MetaboLights
UnknownAutoantibodies in Chinese patients with chronic hepatitis B: prevalence and clinical associations.
Not available
S-EPMC4284347 | biostudies-literature
Unknown(3-Carb-oxy-5-sulfonatobenzoato-κO,O)bis-[2-(2-pyrid-yl)-1H-benzimidazole-κN,N]zinc(II) monohydrate.
Not available
S-EPMC2968999 | biostudies-literature
ProteomicsRepression of PRMT5-mediated dimethylation stabilizes vimentin and promotes metastasis in MTAP-loss lung cancer
Abstract The aggressive nature and poor prognosis of lung cancer led us to explore the mechanisms driving disease progression. Utilizing our invasive cell-based model, we identified methylthioadenosine phosphorylase (MTAP) and confirmed its suppressive effects on tumorigenesis and metastasis, and pa...
ORGANISM(S): Homo sapiens (Human) 
2022-05-31 | PXD031192 | Pride
Human Dimethylation Lung cancer 
MetabolomicsThe trans-omics landscape of COVID-19
The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency. Various omics results have been reported for COVID-19, but the molecular hallmarks of COVID-19, especially in those patients without comorbidities, have not been fully investigated. Here we collect blood samples from 2...
2021-10-06 | MTBLS2542 | MetaboLights
TranscriptomicsAmiloride modulates alternative splicing in leukemic cells and re-sensitizes Bcr-AblT315I mutant cells to imatinib
We have discovered that amiloride can produce a genome-wide effect on alternative splicing of various RNA transcripts, most importantly including those of the apoptotic factors, in K562 leukemic cells. Target was prepared from 4 biological replicates of 0.5 mM amiloride-treatment for 24hr and 3 cont...
ORGANISM(S): Homo sapiens 
2012-09-17 | E-GEOD-24976 | biostudies-arrayexpress
TranscriptomicsCancer-Associated Fibroblasts Support Lung Cancer Stemness through Paracrine IGF-II/IGF1R/Nanog Signaling
The CLS1/CAF co-culture maintained the cancer stemness. This cancer stemness was lost when the CAF feeder cells were removed during passaging. To investigate the specific signaling pathways and markers of lung CSCs, we analyzed the gene expression profile of the CLS1 sphere after CLS1/CAF co-cultur...
ORGANISM(S): Homo sapiens 
2014-03-25 | E-GEOD-38678 | biostudies-arrayexpress
Unknown1,4-Bis(1H-benzimidazol-2-yl)benzene methanol monosolvate.
Not available
S-EPMC3050263 | biostudies-literature
UnknownCFS-1686 causes cell cycle arrest at intra-S phase by interference of interaction of topoisomerase 1 with DNA.
Not available
S-EPMC4252032 | biostudies-literature
Unknown2-[(3-Bromo-anilino)meth-yl]-1,2-benzo-thia-zol-3(2H)-one.
Not available
S-EPMC3344448 | biostudies-literature
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