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Proteomicsthe Effect of Fatty Acids in Hepatic Insulin resistance-part2
Monounsaturated fatty acid (MUFA) oleic acid (OA) has been reported to reverse saturated fatty acid palmitic acid (PA)-induced hepatic insulin resistance (IR). However, the detailed molecular mechanism remains elusive. In addition, previous research also showed that -3 polyunsaturated fatty acid (PU...
ORGANISM(S): Homo sapiens (Human) 
2019-07-11 | PXD012066 | Pride
Human  free fatty acids  insulin resistance  quantitative proteomics  calcium  atp. 
ProteomicsGrass carp SERPINA1 CoIP with hepatopancreas mass spectrometry analysis
SERPINA1, a member of the serine protease inhibitor family, plays a role in viral infection and inflammation by regulating the activities of serine and cysteine proteases. To further investigate the antiviral role SERPINA1 played in GCRV (Grass carp Reovirus) infection, a polyclonal antibody of SERP...
ORGANISM(S): Ctenopharyngodon idella 
2022-08-31 | PXD036356 | Pride
Serpina1 Grass carp Coip/ms Hepatopancreas 
ProteomicsLabel-free proteomics of endometrial epithelial cell for identification of presumptive biomarkers of endometritis
A total of 1180 proteins were identified in the control group and endometritis model group, of which 313 differential proteins were accurately quantified. The proteomic results were verified by WB, TEC and IF techniques, and the same conclusion was obtained.
ORGANISM(S): Capra Hircus 
2022-05-18 | PXD033950 |
ProteomicsProteomic study on lavage fluid of Dairy cows 30 days after delivery
Lipopolysaccharide (LPS) is a component of the outer membrane of gram-negative bacteria that is involved in pathogenic processes leading to postpartum metritis and endometritis in dairy cow. It also causes inflammation of the endometrium. This study aimed to investigate the effects of LPS on cow end...
ORGANISM(S): Bos Taurus 
PXD036248 |
ProteomicsThe Effect of Fatty Acids in Hepatic Insulin Resistance - Part 1
Monounsaturated fatty acid (MUFA) oleic acid (OA) has been reported to restore saturated fatty acid palmitic acid (PA)-induced hepatic insulin resistance (IR). However, the detailed molecular mechanism remains elusive. In addition, -3 polyunsaturated fatty acid (PUFA) such as Eicosapentaenoic acid (...
ORGANISM(S): Homo sapiens (Human) 
2019-07-11 | PXD012065 | Pride
Fatty acids  insulin resistance  pa  epa 
ProteomicsInvestigation of circulating proteomic biomarkers for diagnosis of sporadic Amyotrophic Lateral Sclerosis
To reveal candidate biomarkers for sALS, serum sampled of 10 sALS patients and 5 healthy controls were collected and underwent label-free quantitative proteomics.
ORGANISM(S): Homo Sapiens 
2022-12-01 | PXD038507 |
ProteomicsIntegrated proteomic and transcriptomic analyses reveal the roles of Brucella BI-1 in cell division and membrane homeostasis of Brucella suis S2
To explore the role of Brucella BI-1 in Brucella suis S2, we constructed the Brucella BI-1 deletion mutant strain and its complementary strain. We then determined the effect of Brucella BI-1 deletion on the physiological characteristics of Brucella suis S2 and revealed them via integrated transcript...
ORGANISM(S): Brucella Suis Bv. 1 Str. S2 
2020-11-13 | PXD022537 |
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