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UnknownGab2 mediates hepatocellular carcinogenesis by integrating multiple signaling pathways.
Not available
S-EPMC5690380 | biostudies-literature
TranscriptomicsComplete dosage compensation and sex-biased gene expression in Manduca sexta
Using 4 replicate males and 4 replicate females this experiment examined dosage compensation and sex-biased gene expression. Briefly we performed a de novo assembly of the Manduca sexta transcriptome using all sequenced libraries, quantified genes expression, identified the physical locations of gen...
ORGANISM(S): Manduca sexta 
2014-03-18 | E-MTAB-2066 | biostudies-arrayexpress
TranscriptomicsSolanum lycopersicumTranscriptome or Gene expression
Gene expression in wild-type fruit. Strand-specific RNA-Seq data was used to calculate the gene expression value (RPKM) in four wild-type fruit developmental stages including immature fruit at 17DPA, mature green fruit (seeds development completes) at 39DPA, breaker fruit (onset of ripening) at 42DP...
ORGANISM(S): Solanum lycopersicum 
2011-10-07 | E-MTAB-4818 | biostudies-arrayexpress
MetabolomicsPRODH regultes naive pluripotency by influencing mitochondrial oxidative phosphorylation (Untargeted metabolomics)

Naïve human embryonic stem cells (hESCs) that resemble the pre-implantation epiblasts are fueled by a combination of aerobic glycolysis and oxidative phosphorylation, but their mitochondrial regulators are poorly understood. Here we report that, proline dehydrogenase (PRODH), a mitochondria-local...

2024-02-12 | MTBLS7840 | MetaboLights
MetabolomicsCell Membrane Remodeling Mediates Polymyxin B Resistance in Klebsiella pneumoniae: An Integrated Proteomics and Metabolomics Study
Polymyxin B (PB) is introduced into the clinic as the last-line therapy against carbapenem-resistant Klebsiella pneumoniae (CRKP). Unfortunately, increased resistance to PB in Klebsiella pneumoniae (K. pneumoniae) has threatened global health. Resistance of K. pneumoniae ...
2022-03-04 | MTBLS4132 | MetaboLights
TranscriptomicsGenome-wide miRNA profile of MCF7 cells overexpressing wild-type and mutant miR-222
MCF7 cells were infected with retrovirus to overexpress wild-type and mutant miR-222 Measure miRNA expression level in MCF7 cells after overexpressing wild-type and mutant miR-222
ORGANISM(S): Homo sapiens 
2015-02-05 | E-GEOD-64363 | biostudies-arrayexpress
MetabolomicsAirway Dysbiosis Accelerates Lung Function Decline in Chronic Obstructive Pulmonary Disease (Human UPLC-MS/MS assays)

Progressive decline in lung function is a hallmark of chronic obstructive pulmonary disease (COPD). Although airway dysbiosis occurs in COPD, whether it contributes to disease progression remains unknown. Here, through a longitudinal analysis on 181 COPD individuals from two large cohorts involvi...

2023-06-12 | MTBLS5423 | MetaboLights
MetabolomicsTranscriptomics and metabolomics of engineered Synechococcus elongatus during photomixotrophic growth

BACKGROUND: Converting carbon dioxide (CO2) into value-added chemicals using engineered cyanobacteria is a promising strategy to tackle the global warming and energy shortage issues. However, most cyanobacteria are autotrophic and use CO2 as a sole carbon source, which makes it h...

2022-03-21 | MTBLS2825 | MetaboLights
UnknownAbnormalities in large-scale brain network dynamics in late-life depression with suicidal ideation: an EEG microstate analysis.
Not available
S-EPMC11908788 | biostudies-literature
TranscriptomicsGenome-wide analysis of histone modification, protein-DNA binding, cytosine methylation and transcriptome data in mouse and human ES cells and pig iPS cells
Genome-wide analysis of histone modification (H2AZ, H3K27ac, H3K27me3, H3K36me3, H3K4me1, H3K4me2, H3K4me3 and H3K9me3), protein-DNA binding (TAF1, P300, Pou5f1 and Nanog), cytosine methylation and transcriptome data in mouse and human ES cells and pig iPS cells We generated histone modification da...
ORGANISM(S): Homo sapiens 
2012-02-28 | E-GEOD-36114 | biostudies-arrayexpress
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