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ProteomicsDifferences of phosphoproteome between c-MYC and L-MYC during cellular reprogramming
MYC proteins (c-MYC, n-MYC, and L-MYC) are essential for improving reprogramming efficiency. L-MYC can generate iPSC colonies more efficiently than c-MYC. Still, it remains unknown what is the functional differences between c-MYC and L-MYC during cellular reprogramming. In this study, we performed p...
ORGANISM(S): Homo Sapiens (human) 
2022-01-08 | PXD027078 | JPOST Repository
ProteomicsDifferences of proteome between c-MYC and L-MYC during cellular reprogramming
MYC proteins (c-MYC, n-MYC, and L-MYC) are essential for improving reprogramming efficiency. L-MYC can generate iPSC colonies more efficiently than c-MYC. Still, it remains unknown what is the functional differences between c-MYC and L-MYC during cellular reprogramming. In this study, we performed p...
ORGANISM(S): Homo Sapiens (human) 
2022-01-08 | PXD027079 | JPOST Repository
ProteomicsDifferences in binding partners between c-MYC and L-MYC during cellular reprogramming
MYC proteins (c-MYC, n-MYC, and L-MYC) are essential for improving reprogramming efficiency. L-MYC can generate iPSC colonies more efficiently than c-MYC. Still, it remains unknown what is the functional differences between c-MYC and L-MYC during cellular reprogramming. In this study, we performed p...
ORGANISM(S): Homo Sapiens (human) 
2022-01-07 | PXD027083 | JPOST Repository
ProteomicsDifferences in protein domains between c-MYC and L-MYC during cellular reprogramming
MYC proteins (c-MYC, n-MYC, and L-MYC) are essential for improving reprogramming efficiency. L-MYC can generate iPSC colonies more efficiently than c-MYC. Still, it remains unknown what is the functional differences between c-MYC and L-MYC during cellular reprogramming. In this study, we performed p...
ORGANISM(S): Homo Sapiens (human) 
2022-01-07 | PXD027086 | JPOST Repository
TranscriptomicsDifferentially regulated genes in control and c-myc N-myc deficient LT-HSCs
Analysis of HSCs from control and c-myc N-myc deficient long-term hematopoietic stem cells. HSCs lacking both c-myc and N-myc display increased apoptosis rates. Data provide insight into the molecular changes occuring upon complete loss of Myc activity, clarifying the resulting apoptotic mechanism a...
ORGANISM(S): Mus musculus 
2009-02-20 | E-GEOD-12467 | biostudies-arrayexpress
Proteomicsc-di-GMP affect the protein acetylation through CobB dependent deacetylation
To determine whether c-di-GMP could affect CobB-dependent deacetylation in a global setting, we applied Stable Isotope Labeling with Amino acids in Cell culture (SILAC) coupled with MS to quantitatively compare the levels of protein acetylation in WT, ΔcobB and ΔdgcZ cells.
ORGANISM(S): Escherichia coli 
2019-06-17 | PXD013292 | Pride
C-di-gmp cobb 
TranscriptomicsTranscription profiling of human HEK293 cells transfected with either wild type or delta exon 4 mutants of surfacant protein C
Mutations in the gene encoding surfactant protein C (SFTPC) have been linked to interstitial lung disease in children and adults. Expression of the index mutation, SP-Cdeltaexon4, in transiently transfected cells and type II cells of transgenic mice resulted in misfolding of the proprotein, activat...
ORGANISM(S): Homo sapiens 
2007-09-28 | E-GEOD-2980 | biostudies-arrayexpress
ProteomicsSILAC labeling efficiency for c-di-GMP and CobB
Description To determine whether c-di-GMP could affect CobB-dependent deacetylation in a global setting, we applied Stable Isotope Labeling with Amino acids in Cell culture (SILAC) coupled with MS to quantitatively compare the levels of protein acetylation in WT, ΔcobB and ΔdgcZ cells. Before that, ...
ORGANISM(S): Escherichia coli 
2019-06-24 | PXD014344 | Pride
Silac c-di-gmp 
ProteomicsExpression of a surfactant protein C mutation impairs postnatal expansion of alveolar type 2 epithelial cells leading to permanent cell loss and decreased repair capacity in adult lungs
Mutations in the gene encoding surfactant protein C (SFTPC) are associated with interstitial lung disease in children and adults. To assess the natural history of disease, we knocked-in a familial, disease-associated SFTPC mutation, L188Q (L184Q in mice), into the mouse Sftpc locus. Expression of th...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-08-19 | MSV000085976 | MassIVE
UnknownCharacterization of the complete chloroplast genome of Carya hunanensis W. C. Cheng & R. H. Chang.
Not available
S-EPMC7832538 | biostudies-literature
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