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Metabolomics13C glucose labelling studies using 2D NMR is a useful tool for determining ex vivo whole organ metabolism during hypothermic machine perfusion of kidneys
Background: The aim of this study is to determine the feasibility of using Nuclear Magnetic Resonance (NMR) tracer studies (13C-enriched glucose) to detect ex vivo de novo metabolism in the perfusion fluid and cortical tissue of porcine kidneys during hypothermic machine perfusion (HMP). Methods: Po...
2017-10-16 | MTBLS367 | MetaboLights
MetabolomicsMicrobial liberation of N-methylserotonin from orange fiber in gnotobiotic mice and humans
Plant fibers in byproduct streams produced by non-harsh food processing methods represent biorepositories of diverse, naturally occurring, and physiologically active biomolecules. To demonstrate one approach for their characterization, mass spectrometry of intestinal contents from gnotobiotic mice, ...
2022-07-28 | MTBLS2331 | MetaboLights
TranscriptomicsDox-regulated Notch4 overexpression in mouse ES cells redirects hemagioblasts to a cardiac fate.
Previous studies have demonstrated that distinct progenitor subpopulations of mesoderm display tissue specific and vascular potential: hemangioblasts, a progenitor population capable of generating cells of the hematopoietic, endothelial and vascular smooth muscle lineages, and a multipotential proge...
ORGANISM(S): Mus musculus 
2010-09-15 | E-GEOD-12425 | biostudies-arrayexpress
MetabolomicsUntargeted metabolomics analyses and contaminant chemistry of Dreissenid mussels at the Maumee River Area of Concern in the Great Lakes

Bivalves serve as an ideal ecological indicator; hence, their use by the NOAA Mussel Watch Program to monitor environmental health. This study aimed to expand the baseline knowledge of using metabolic end points in environmental monitoring by investigating the dreissenid mussel metabolome in the ...

2024-06-03 | MTBLS6311 | MetaboLights
TranscriptomicsTranscription profiling of mouse deficient for Fibrillin-1
Different fibrillin-1 mutant mice
ORGANISM(S): Mus musculus 
2008-06-11 | E-GEOD-1852 | biostudies-arrayexpress
ProteomicsProteome-Level Functional Redundancy in the Human Gut Microbiome
Here, we quantify the proteome-level functional redundancy in the human gut microbiome using metaproteomics and network approaches.In particular, we used an ultra-deep metaproteomics approach based on high-pH reverse phase fractionation. The data analysis revealed high protein-level functional redun...
ORGANISM(S): human gut metagenome 
2023-06-08 | PXD027297 | Pride
Gut microbiome Network Functional redundancy Metaproteomics 
UnknownTransparent antifouling material for improved operative field visibility in endoscopy.
Not available
S-EPMC5081611 | biostudies-literature
ProteomicsMurine hippocampal proteome - Phosphoproteome Profiling Reveals Circadian Clock Regulation of Posttranslational Modifications in the Murine Hippocampus
The circadian clock is an endogenous oscillator that drives daily rhythms in physiology, behavior and gene expression. The underlying mechanisms of circadian timekeeping are cell-autonomous and involve interconnecting transcription-translation feedback loops. The hippocampus plays an important role ...
ORGANISM(S): Mus musculus (Mouse) 
2017-04-11 | PXD005668 | Pride
Lc-msms Mouse Hippocampus Proteome 
ProteomicsMurine hippocampal phosphoproteome LC-MSMS
The hippocampus plays an important role in spatial memory and the conversion of short-term to long-term memory. Several studies have reported the presence of a peripheral oscillator in the hippocampus, and have highlighted the importance of circadian regulation in memory formation. In this study we ...
ORGANISM(S): Mus musculus (Mouse) 
2017-04-11 | PXD005669 | Pride
Circadian Hippocampus Phosphoproteome Mouse 
ProteomicsA human gut microbiome treated in vitro with Diclofenac
One individual microbiome was cultured with or without the presence of diclofenac (an NSAID drug) in triplicates using RapidAIM assay.
ORGANISM(S): human gut metagenome 
2022-06-23 | PXD033624 | Pride
In vitro culture Drug treatment Human gut microbiome 
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