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The SCH9 null strain has smaller cell size, grows at a slower rate and survives three times longer than wide-type yeast. This study aims to dissect the mechanisms that lead to the yeast life span extension of sch9-delta. We measure gene expression profiles of the S. cerevisiae wild type and the lon...
ORGANISM(S): Saccharomyces cerevisiae 
Pentacyclic triterpenes are a class of natural products that are present in Dipsacus asperoides with a long history of use. Pharmacological studies have shown that pentacyclic triterpenes have various biological activities. We have performed proteomic analysis in multiple tissues of this species to ...
ORGANISM(S): Dipsacus asperoides 
2023-02-09 | PXD038580 | Pride
Alcoholic fatty liver disease (AFLD) is a liver disease closely related to long-term alcohol consumption. Although it is known that liver microsomal cytochrome P450 enzyme (CYP450) plays a crucial role in metabolizing alcohol and various exogenous compounds, the specific mechanism by which alcohol a...
ORGANISM(S): Mus Musculus 
Plant fibers in byproduct streams produced by non-harsh food processing methods represent biorepositories of diverse, naturally occurring, and physiologically active biomolecules. To demonstrate one approach for their characterization, mass spectrometry of intestinal contents from gnotobiotic mice, ...
2022-07-28 | MTBLS2331 | MetaboLights
To understand the role of long non-coding RNAs and interaction with coding RNAs in bladder urothelial cell carcinoma (BUCC), we performed genome-wide screening long non-coding RNAs and coding RNAs expression on primary BUCC tissues and normal tissues using long non-coding RNA array (Agilent platef...
ORGANISM(S): Homo sapiens 
Plants grown at high densities perceive a decrease in the red to far-red (R:FR) ratio of incoming light, resulting from absorption of red light by canopy leaves and reflection of far-red light from neighboring plants. These changes in light quality trigger a series of responses known collectively as...
ORGANISM(S): Arabidopsis thaliana 
Successful ex vivo expansion of hematopoietic stem cells (HSCs) would greatly benefit the treatment of disease and the understanding of critical questions of stem cell biology. Microarray studies showed that the HSC supportive mouse fetal liver CD3+ cells specifically expressed angiopoietin-like 2 (...
ORGANISM(S): Mus musculus 
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