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Analysis of HSCs from control and c-myc N-myc deficient long-term hematopoietic stem cells. HSCs lacking both c-myc and N-myc display increased apoptosis rates. Data provide insight into the molecular changes occuring upon complete loss of Myc activity, clarifying the resulting apoptotic mechanism a...
ORGANISM(S): Mus musculus 
The woodchuck model of hepatitis B virus (HBV) infection displays many characteristics of human infection and has particular value for characterizing the host immune responses during the development of chronic infection. Using the newly developed custom woodchuck microarray platform, we compared the...
ORGANISM(S): Marmota monax 
Looking at the expression of ER alpha in BRCA1 and mutant tumours
ORGANISM(S): Homo sapiens 
Due to increasing evidence of the complexity of the transcriptome, we have, through a combination of cDNA sequencing, gene expression profiling and public sequence data mining, characterized the transcriptome of Non-Small Cell Lung Carcinoma. We used this information to create a unique disease focus...
ORGANISM(S): Homo sapiens 
Microarray analysis has been useful for identifying the targets of many transcription factors. However, gene expression changes in response to transcription factor perturbation reveal both direct transcriptional targets and secondary gene regulation. By integrating RNA interference, gene expression ...
ORGANISM(S): Homo sapiens 
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