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TranscriptomicsRNA-seq of neuronal SOX2-ablated murine suprachiasmatic nuclei against wild-type littermate controls
Mice lacking the stem/progenitor cell transcription factor, Sex determining region Y-box 2 (SOX2), in neurons of the suprachiasmatic nuclei display imprecise, poorly consolidated behavioral rhythms that do not entrain efficiently to environmental light cycles. RNA sequencing revealed that Sox2 defic...
ORGANISM(S): Mus musculus 
2019-03-18 | E-MTAB-7496 | biostudies-arrayexpress
MetabolomicsTranscriptomic and metabolomic analyses reveal the differential accumulation of phenylpropanoids and terpenoids in hemp autotetraploid and its diploid progenitor

Background

Cannabis sativa, a dioecious plant that has been cultivated worldwide for thousands of years, is known for its secondary metabolites, especially cannabinoids, which possess several medicinal effects. In this study, we investigated the autopolyploidization effects on the biosynthes...
2023-09-21 | MTBLS6032 | MetaboLights
UnknownTransperitoneal vs retroperitoneal laparoscopic radical nephrectomy: a double-arm, parallel-group randomized clinical trial.
Not available
S-EPMC10838419 | biostudies-literature
UnknownDevelopment and validation of a nomogram for predicting overall survival in patients with early-onset endometrial cancer.
Not available
S-EPMC10720131 | biostudies-literature
MetabolomicsPRODH regultes naive pluripotency by influencing mitochondrial oxidative phosphorylation (Targeted metabolomics)

Naïve human embryonic stem cells (hESCs) that resemble the pre-implantation epiblasts are fueled by a combination of aerobic glycolysis and oxidative phosphorylation, but their mitochondrial regulators are poorly understood. Here we report that, proline dehydrogenase (PRODH), a mitochondria-local...

2024-02-12 | MTBLS7832 | MetaboLights
MetabolomicsPRODH regultes naive pluripotency by influencing mitochondrial oxidative phosphorylation (Untargeted metabolomics)

Naïve human embryonic stem cells (hESCs) that resemble the pre-implantation epiblasts are fueled by a combination of aerobic glycolysis and oxidative phosphorylation, but their mitochondrial regulators are poorly understood. Here we report that, proline dehydrogenase (PRODH), a mitochondria-local...

2024-02-12 | MTBLS7840 | MetaboLights
UnknownIsolation and characterization of WUPyV in polarized human airway epithelial cells.
Not available
S-EPMC7344044 | biostudies-literature
UnknownTricistronic hepatitis C virus subgenomic replicon expressing double transgenes.
Not available
S-EPMC4277965 | biostudies-literature
UnknownWhole genome sequencing and evolution analyses of Human metapneumovirus.
Not available
S-EPMC10164418 | biostudies-literature
UnknownAntioxidant, antihyperglycemic, and antihyperlipidemic properties of Chimonanthus salicifolius S. Y. Hu leaves in experimental animals: modulation of thioredoxin and glutathione systems, renal water reabsorption, and gut microbiota.
Not available
S-EPMC10176510 | biostudies-literature
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