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TranscriptomicsAberrant global methylation patterns affect the molecular pathogenesis and prognosis of human multiple myeloma
We have used genome-wide methylation microarrays to analyze differences in CpG methylation patterns in cells relevant to the pathogenesis of myeloma plasma cells, including B cells, normal plasma cells, MGUS, presentation myeloma, and plasma cell leukemia (PCL). We show that methylation patterns in ...
ORGANISM(S): Homo sapiens 
2010-10-18 | E-GEOD-21304 | biostudies-arrayexpress
TranscriptomicsA compendium of myeloma associated chromosomal copy number abnormalities and their prognostic value
To obtain a comprehensive genomic profile of presenting multiple myeloma cases we performed high resolution single nucleotide polymorphism (SNP) mapping array analysis in 114 samples alongside 258 samples analysed by U133 Plus 2.0 expression array (Affymetrix). We examined DNA copy number alteratio...
ORGANISM(S): Homo sapiens 
2010-11-02 | E-GEOD-21349 | biostudies-arrayexpress
UnknownGender disparities in the tumor genetics and clinical outcome of multiple myeloma.
Not available
S-EPMC4545514 | biostudies-literature
UnknownProfound parental bias associated with chromosome 14 acquired uniparental disomy indicates targeting of an imprinted locus.
Not available
S-EPMC4687469 | biostudies-literature
UnknownMapping of chromosome 1p deletions in myeloma identifies FAM46C at 1p12 and CDKN2C at 1p32.3 as being genes in regions associated with adverse survival.
Not available
S-EPMC5751883 | biostudies-literature
UnknownDeletions of CDKN2C in multiple myeloma: biological and clinical implications.
Not available
S-EPMC2581792 | biostudies-literature
UnknownA novel prognostic model in myeloma based on co-segregating adverse FISH lesions and the ISS: analysis of patients treated in the MRC Myeloma IX trial.
Not available
S-EPMC4545515 | biostudies-literature
UnknownA molecular diagnostic approach able to detect the recurrent genetic prognostic factors typical of presenting myeloma.
Not available
S-EPMC4310140 | biostudies-literature
UnknownTransmission of diffuse large B-cell lymphoma by an allogeneic stem-cell transplant.
Not available
S-EPMC6442949 | biostudies-literature
UnknownTP53 Mutations Identified Using NGS Comprise the Overwhelming Majority of TP53 Disruptions in CLL: Results From a Multicentre Study.
Not available
S-EPMC9273895 | biostudies-literature
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