Sort   by:  
 Page size 
MetabolomicsMetabolomics Insights in Early Childhood Caries
Dental caries is characterized by a dysbiotic shift at the biofilm-tooth surface interface, yet comprehensive biochemical characterizations of the biofilm are scant. We used metabolomics to identify biochemical features of the supragingival biofilm associated with early childhood caries (ECC) preval...
2021-01-29 | MTBLS2215 | MetaboLights
MetabolomicsPolymicrobial detection and metabolomics in saliva of children with early childhood caries

Cariogenic microorganisms as well as salivary metabolic status in early childhood caries (ECC) have been reported to differ from that in adult caries. The main aim of this study was to identify specific microbial species and salivary metabolites in children with ECC using species-specific qPCR an...

2024-11-12 | MTBLS10890 | MetaboLights
MetabolomicsA longitudinal ¹H NMR-based urinary metabolomics dataset in a birth cohort for childhood atopic diseases

This dataset presents longitudinal urinary metabolomic profiles from 198 children at 1 month, 6 months, 1 year, 3 years and 5 years. It includes demographic data, feeding practices, parental atopy, household income and atopic disease status over time. Total and allergen-specific IgE (mite, egg, c...

2025-07-28 | MTBLS12785 | MetaboLights
TranscriptomicsTranscription profiling of human diagnostic samples from children with NCI high risk B-precursor ALL treated on the protocol COG 1961 to investigate early response and outcome in high-risk childhood acute lymphoblastic leukemia
The cure rate for childhood ALL has improved considerably in part because therapy is routinely tailored to the predicted risk of relapse. Various clinical and laboratory variables are used in current risk-stratification schemes, but many children who fail therapy lack adverse prognostic factors at i...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7440 | biostudies-arrayexpress
ProteomicsProteogenomics of High hyperdiploid childhood acute lymphoblastic leukemia
Proteogenomic analysis and genomic profiling, RNA-sequencing, and mass spectrometry-based analysis of High hyperdiploid childhood acute lymphoblastic leukemia.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-01-29 | MSV000084862 | MassIVE
TranscriptomicsGlucocorticoid effect on mRNA translation in childhood acute lymphoblastic leukemia
Glucocorticoids (GCs) are a central component in treating childhood acute lymphoblastic leukemia (chALL). They mainly act via regulating gene transcription. However, control of mRNA translation by GC has never been assessed systematically. In our research, T- and precursor B-ALL cells were cultured ...
ORGANISM(S): Homo sapiens 
2013-12-03 | E-GEOD-48680 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of resistant acute lymphoblastic leukemia ALL
Treatment resistance as indicated by the presence of high levels of minimal residual disease (MRD) after induction therapy and induction consolidation is associated with a poor prognosis in childhood acute lymphoblastic leukemia (ALL). We hypothesized that treatment resistance is an intrinsic featur...
ORGANISM(S): Homo sapiens 
2005-11-09 | E-SMDB-2922 | biostudies-arrayexpress
TranscriptomicsGermline genomic variations associated with childhood acute lymphoblastic leukemia
We identified germline single nucleotide polymorphisms (SNPs) associated with childhood acute lymphoblastic leukemia (ALL) and its subtypes. Using the Affymetrix 500K Mapping array and publicly available genotypes, we identified 18 SNPs whose allele frequency differed (P<1x10-5) between a pediatric...
ORGANISM(S): Homo sapiens 
2009-08-16 | E-GEOD-17195 | biostudies-arrayexpress
TranscriptomicsEpigenetic landscape correlates with genetic subtype but does not predict outcome in childhood acute lymphoblastic leukemia
We analyzed 52 Diagnostic samples from childhood Acute lymphoblastic leukemia samples We compared methylation profiles with four ALL cytogentic subtypes using (n=26) long term remission vs. (n=26) that went on to relapse
ORGANISM(S): Homo sapiens 
2015-08-11 | E-GEOD-69229 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human ALL samples for patients included in the Dutch Childhood Oncology Group
Childhood acute lymphoblastic leukemia (ALL) comprises a large group of genetic subtypes with a favorable prognosis characterized by a TEL-AML1-fusion, hyperdiploidy (>50 chromosomes) or E2A-PBX1 fusion and a smaller group with unfavorable outcome characterized by either a BCR-ABL-fusion, MLL-rearr...
ORGANISM(S): Homo sapiens 
2009-02-01 | E-GEOD-13351 | biostudies-arrayexpress
Sort   by:  
 Page size