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MetabolomicsInvestigating exposures and health impacts of endocrine disrupting chemicals among inner-city children.
Not available
ORGANISM(S): Homo sapiens 
ST001383 | MetabolomicsWorkbench
TranscriptomicsDNA methylation in oesophageal biopsies of children diagnosed with Eosinophilic Oesophagitis (EoE) and controls
Eosinophilic oesophagitis (EoE) is a leading cause of dysphagia and food impaction in children and adults. In this pilot study, we performed genome-wide DNA methylation analyses on oesophageal biopsies obtained from children diagnosed with EoE (at diagnosis and after treatment) and matched controls....
ORGANISM(S): Homo sapiens 
2021-07-01 | E-MTAB-9824 | biostudies-arrayexpress
TranscriptomicsAn early inflammatory gene profile in visceral adipose tissue in children
The aim of this study was to characterize expression profiles of visceral and subcutaneous adipose tissue in children. Adipose tissue samples were collected from children having elective surgery (n=71, [54 boys], 6.0 +- 4.3 years). Affymetrix microarrays (n=20) were performed to characterize the fun...
ORGANISM(S): Homo sapiens 
2011-06-04 | E-GEOD-29718 | biostudies-arrayexpress
TranscriptomicsPaired whole blood human transcription profiles from children with severe malaria and mild malaria
Whole blood transcriptomes from a longitudinal study of 5 Malawian children who first present with severe Plasmodium falciparum malaria, and return in one month with mild malaria We used microarrays to identify transcripts that were associated with each clinical presentation. A blood sample was tak...
ORGANISM(S): Homo sapiens 
2012-01-11 | E-GEOD-33811 | biostudies-arrayexpress
TranscriptomicsHost response transcriptional profiling of typhoid fever infected Nigerian children
We were able to obtain distinct gene expression profile between children with typhoid fever and other bacteremic infections. Peripheral blood of Nigerian children with typhoid fever and other bacteremic infection were obtained in Paxgene tubes. Total RNa were extracted using Paxgene blood RNA kit a...
ORGANISM(S): Homo sapiens 
2011-11-29 | E-GEOD-28658 | biostudies-arrayexpress
TranscriptomicsGenome-wide espression kinetics of children progressing to clinical Type 1 diabetes (T1D).
To unravel genes and molecular pathways involved in the pathogenesis of type 1 diabetes (T1D), we performed genome-wide gene expression profiling of prospective venous blood samples from children developing T1D-associated autoantibodies or progressing towards clinical diagnosis. 247 peripheral blood...
ORGANISM(S): Homo sapiens 
2014-02-20 | E-GEOD-30210 | biostudies-arrayexpress
TranscriptomicsGenome-wide expression kinetics of children with T1D-associated autoantibodies compared to healthy matched controls II
To unravel genes and molecular pathways involved in the pathogenesis of type 1 diabetes (T1D), we performed genome-wide gene expression profiling of prospective venous blood samples from children developing T1D-associated autoantibodies or progressing towards clinical diagnosis. 58 peripheral blood ...
ORGANISM(S): Homo sapiens 
2014-02-20 | E-GEOD-30209 | biostudies-arrayexpress
ProteomicsUpper airway proteomes of infants and children in sub-Saharan Africa
Mass spectrometry-based proteomics was carried out on Naso- and oropharyngeal swabs collected from infants and children presenting to hospital with both mild and severe respiratory illnesses as well as age-matched control children who were well and sampled from home.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-04-04 | MSV000082238 | MassIVE
ProteomicsSerum APOC1 levels are decreased in young autoantibody positive children who rapidly progress to type 1 diabetes
Aims/hypothesis: Biomarkers are needed to accurately predict and monitor type 1 diabetes progression during the substantially heterogeneous presymptomatic period of the disease development. To address this concern, we studied temporal changes in the plasma and serum proteomes of < 5-year-old childre...
ORGANISM(S): Homo Sapiens 
PXD033946 | panorama
TranscriptomicsTranscription profiling of human PBMCs from children infected with rotavirus in acute and convalescent phase reveals rotavirus infection alters peripheral T-cell homeostasis in children with acute diarrhea
Rotavirus infection is the single most important cause of severe diarrhea in young children worldwide. We used Affymetrix Human U95Av2 high density oligonucleotide arrays to compare gene expression profiles in peripheral blood mononuclear cells (PBMC) of 10 children with acute rotavirus diarrhea and...
ORGANISM(S): Homo sapiens 
2007-11-01 | E-GEOD-2729 | biostudies-arrayexpress
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