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UnknownSelection of chemically defined media for CHO cell fed-batch culture processes.
Not available
S-EPMC5264622 | biostudies-literature
Transcriptomicsshoots and roots treated with methotrexate and 5-formyl-thf-Transcriptomic and metabolic changes in Arabidopsis thaliana supplemented with 5-CHO-THF and its relationship with the accumulation and transformation to THF active derivatives
au11-02_cho-thf - shoots and roots treated with methotrexate and 5-formyl-thf - Folates and 1C metabolism - The objective of this study is to investigate the changes on the plant expression profiles due to 5-CHO-THF assimilation and transformation. Additionally, plants supplemented with methotrexate...
ORGANISM(S): Arabidopsis thaliana 
2013-08-01 | E-GEOD-41406 | biostudies-arrayexpress
TranscriptomicsInterplay of choline metabolites and genes in patient-derived breast cancer xenografts
Dysregulated choline metabolism is a well-known feature of breast cancer, but the underlying mechanisms are not fully understood. In this study, the metabolomic and transcriptomic characteristics of a large panel of human breast cancer xenograft models were mapped, with focus on choline metabolism. ...
ORGANISM(S): Homo sapiens 
2014-01-16 | E-GEOD-44666 | biostudies-arrayexpress
TranscriptomicsCXCR4 activation maintains a stem cell population in tamoxifen-resistant breast cancer cells through AHR signaling
Targeting the estrogen signaling pathway has proved to be of great value in the treatment of human breast cancer. Tamoxifen, a selective estrogen receptor modulator (SERM), is the most widely used antiestrogen. However, only 40-50% of patients with estrogen receptor (ER) positive breast cancer benef...
ORGANISM(S): Homo sapiens 
2012-12-21 | E-GEOD-31831 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human 48 clinical breast cancer arrays to perform statistical identification of gene association by CID in application of constructing ER regulatory network
A variety of high-throughput techniques are now available for constructing comprehensive gene regulatory networks in systems biology. In this study, we report a new statistical approach for facilitating in silico inference of regulatory network structure. The new measure of association, coefficient ...
ORGANISM(S): Homo sapiens 
2009-07-19 | E-GEOD-17041 | biostudies-arrayexpress
UnknownAn Afferent Neuropeptide System Transmits Mechanosensory Signals Triggering Sensitization and Arousal in C. elegans.
Not available
S-EPMC6162336 | biostudies-literature
ProteomicsIdentification of CDK1 phosphorylation of TFCP2L1 from murine embryonic stem cells and bladder cancer cells
Molecular programs involved in embryogenesis are frequently upregulated in oncogenic dedifferentiation and metastasis. However, their precise roles and regulatory mechanisms remain elusive. Here, we showed that CDK1 phosphorylation of TFCP2L1, a pluripotency-associated transcription factor, orches...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2019-11-08 | PXD015635 | Pride
Pluripotency Cdk1 Stemness features Embryonic stem-cell Bladder cancer 
ProteomicsIntegrated Analysis of Global Proteome and Phosphoproteome in Cisplatin Resistant Bladder Cancer Cell Revealed the Molecular Signature Predictive to Patient Survival
Cisplatin-based chemotherapy is the standard care regimen in bladder cancer (BC). However, resistance to the therapy whose molecular mechanisms of the resistance are not fully elucidated rapidly develops in BC patients. Here we introduced multidimensional proteomic analysis providing different level...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD005308 | Pride
Phosphoproteomics Bladder cancer Cisplatin resistance Biological network Molecular signature 
UnknownPhospholipase C in living cells: activation, inhibition, Ca2+ requirement, and regulation of M current.
Not available
S-EPMC2266577 | biostudies-literature
UnknownProtection of c-Fos from autophagic degradation by PRMT1-mediated methylation fosters gastric tumorigenesis.
Not available
S-EPMC10411464 | biostudies-literature
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