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TranscriptomicsUC San Diego_Friedmann_Kang_ESD3_Neuronal Differentiation
The overall gene expression pattern of HPRT knockdown murine D3 stem cells during neuronal differentiation was invesitigated by microarray based gene expression analysis and the results were interpreted by GO, GSEA and signaling pathway analyses with GeneSpring GX and PANTHER Classification System. ...
ORGANISM(S): Mus musculus 
2012-11-22 | E-GEOD-42453 | biostudies-arrayexpress
MetabolomicsShort-term changes in the serum metabolome after laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass

INTRODUCTION: Bariatric surgery is known to be the most effective treatment for weight loss in obese patients and for the rapid remission of obesity-related comorbidities. These short-term improvements result from not only limited digestion or absorption but also dynamic changes ...

2022-03-17 | MTBLS2472 | MetaboLights
ProteomicsAn integrative proteomic approach during Alzheimer’s disease progression in Tau PS19 mice
Alzheimer's disease (AD) is a slowly progressive neurodegenerative disease associated with cognitive, functional, and behavioral impairments characterized by the progressive accumulation of extracellular amyloid-beta plaques and intracellular neurofibrillary tangles of hyperphosphorylated tau protei...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-15 | PXD066515 | Pride
TranscriptomicsProtein translation as major target for gene expression control of O. tsutsugamushi
Orientia tsutsugamushi, an obligate intracellular bacterium, is the causative agent of Scrub typhus. The bacterium can replicate both in its arthropod host and in mammals, including humans. The control mechanisms for bacterial gene expression within eukaryotic host cells are largely unknown. Previou...
ORGANISM(S): Orientia tsutsugamushi 
2010-06-05 | E-GEOD-16966 | biostudies-arrayexpress
ProteomicsRepurposing the antiplatelet drug prasugrel for Parkinson’s disease: Evidence of neuroprotective effects and proteomic profiles
Chronic neuroinflammation is a hallmark pathological feature of Parkinson’s disease (PD) that contributes to progressive neuronal death. Current medications are largely palliative, underscoring the need for alternative therapeutic strategies. Drug repurposing offers a cost-effective and time-efficie...
ORGANISM(S): Mus musculus (Mouse) Rattus norvegicus (Rat) 
2026-07-16 | PXD076315 | Pride
Prasugrel Drug repurposing Proteomics Parkinson’s disease 
UnknownEffect of post-transplant glycemic control on long-term clinical outcomes in kidney transplant recipients with diabetic nephropathy: A multicenter cohort study in Korea.
Not available
S-EPMC5906016 | biostudies-literature
GenomicsAKT phosphorylates H3-threonine 45 to facilitate termination of gene transcription in response to DNA damage.
Purpose: In this study, we show that DNA damage-activated AKT phosphorylates threonine 45 of core histone H3 (H3-T45) Result: By genome-wide chromatin immunoprecipitation sequencing (ChIP-seq) analysis, H3-T45 phosphorylation was distributed throughout DNA damage-responsive gene loci, particularly i...
ORGANISM(S): Homo sapiens 
2015-04-09 | E-GEOD-67699 | biostudies-arrayexpress
TranscriptomicsFunctional modulation of dendritic cells (DCs) by photo-switchable generation of intracellular ROS
This experiment was performed to estimate the difference between DCs stimulated with intracellular ROS or LPS. Total RNA obtainded from DCs stimulated with intracellular ROS or LPS was analyzed for transcriptome
ORGANISM(S): Mus musculus 
2012-11-24 | E-GEOD-42476 | biostudies-arrayexpress
GenomicsChIP_seq
Ctbp2 regulates exit from pluripotency via silencing of embryonic stem cell active genes during differentiation. We mapped the genome-wide occupancy of Ctbp2 by ChIP-seq in mESC (E14).
ORGANISM(S): Mus musculus 
2015-06-30 | E-MTAB-2002 | biostudies-arrayexpress
TranscriptomicsE14RNA-seq
Ctbp2 regulates exit from pluripotency via silencing of embryonic stem cell active genes during differentiation. Gene expression profiles were analyzed for wild-type and Ctbp2-knockdown ESCs at both fferentiated(+LIF) and undifferentiated(-LIF) state.
ORGANISM(S): Mus musculus 
2014-12-31 | E-MTAB-2030 | biostudies-arrayexpress
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