Sort   by:  
 Page size 
TranscriptomicsTo identify genes responsive to treatment with the HIF2a inhibitor PT2399
HIF2a function is both necessary and sufficient for the growth of VHL-null clear cell Renal Cell Carcinoma (ccRCC). Targeting HIF2a function can therefore be a promising therapeutic strategy. We used microarray analysis to characterize a novel pharmacological inhibitor of HIF2a named PT2399. By comp...
ORGANISM(S): Homo sapiens 
2016-07-03 | E-GEOD-72959 | biostudies-arrayexpress
UnknownTetrahedral triple-Q magnetic ordering and large spontaneous Hall conductivity in the metallic triangular antiferromagnet Co1/3TaS2.
Not available
S-EPMC10724158 | biostudies-literature
TranscriptomicsIdentification of pathogenic microRNAs in Helicobacter pylori-associated gastric cancer
To identify dysregulated miRNA(s) upon infection with H. pylori during different pre-malignant and malignant stages of gastric cancer in a mouse model miRNA expression in pre-neoplastic and neoplastic lesions in murine stomachs induced by H. pylori and N-methyl-N-nitrosourea (MNU) after 12 months wa...
ORGANISM(S): Mus musculus 
2015-03-04 | E-GEOD-62503 | biostudies-arrayexpress
ProteomicsDefining super-enhancer landscape in triple-negative breast cancer by multiomic profiling
Here we apply integrated epigenomic and transcriptomic profiling to uncover super-enhancer heterogeneity between breast cancer subtypes, and provide clinically relevant biological insights towards TNBC. Using CRISPR/Cas9-mediated gene editing, we identify genes that are specifically regulated by TNB...
ORGANISM(S): Homo Sapiens 
2021-03-04 | PXD024505 |
UnknownApplication of Deuterium in an M<sub>1</sub> Positive Allosteric Modulator Back-Up Program: The Discovery of VU6045422.
Not available
S-EPMC12006963 | biostudies-literature
TranscriptomicsExpression analysis of superior cervical ganglion from backcrossed TH-MYCN transgenic mice
Neuroblastoma susceptibility in TH-MYN mice is heavily influence by mouse strain background. We have combined linkage analysis of tumor susceptibility with expression QTL analysis of superior cervical ganglia (pure peripheral symptathetic nervous tissue) to identify genes underlying tumor formation...
ORGANISM(S): Mus musculus 
2015-01-30 | E-GEOD-59675 | biostudies-arrayexpress
UnknownMYH9 is a major-effect risk gene for focal segmental glomerulosclerosis.
Not available
S-EPMC2827354 | biostudies-literature
UnknownCytogenetic prognostication within medulloblastoma subgroups.
Not available
S-EPMC3948094 | biostudies-literature
GenomicsGenomic Analysis of Pediatric Low Grade Gliomas

Pediatric low-grade gliomas (PLGGs) are among the most common solid tumors in children but, apart from mutations or duplications in the BRAF kinase in specific subclasses, few genetic driver events are known. Diffuse PLGGs compose a set of uncommon subtypes that exhibit invasive growth and are th...

phs000614.v1.p1 | EGA
UnknownNon-obstructive high-risk plaques increase the risk of future culprit lesions comparable to obstructive plaques without high-risk features: the ICONIC study.
Not available
S-EPMC7440964 | biostudies-literature
Sort   by:  
 Page size