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TranscriptomicsTranscription profiling of Drosophila myoblasts from wild type embryos and twelve genotypes in which myogenesis was selectively perturbed to determine the molecular identities of distinct myoblast subpopulations
An important but largely unmet challenge in understanding the mechanisms that govern formation of specific organs is to decipher the complex and dynamic genetic programs exhibited by the diversity of cell types within the tissue of interest. Here, we use an integrated genetic, genomic and computati...
ORGANISM(S): Drosophila melanogaster 
2007-08-14 | E-GEOD-3854 | biostudies-arrayexpress
UnknownThe hypertrophic cardiomyopathy myosin mutation R453C alters ATP binding and hydrolysis of human cardiac β-myosin.
Not available
S-EPMC3931073 | biostudies-literature
UnknownRevealing the effect of Nb or V doping on anode performance in Na2Ti3O7 for sodium-ion batteries: a first-principles study† † Electronic supplementary information (ESI) available: Table for Lowdin charge of atoms, and figures of optimized structures of the intermediate phase with the lowest energy, orbital-resolved partial density of states, and integrated local density of states. See DOI: https://doi.org/10.1039/d3ra01755a
Not available
S-EPMC10240172 | biostudies-literature
TranscriptomicsTranscription profiling of uterus from 129/SvImJ wildtype mice treated with progesterone
Female mice used were 129/SvImJ wildtype (Jackson Lab), 10-16 weeks; of age. 14 days after ovariectomy, mice were injected; subcutaneously with progesterone dissolved in sesame oil (Sigma;; 0.2mg/0.1mL/mouse), followed by sacrifice and removal of uterine; horns at various times after injection. 8 ...
ORGANISM(S): Mus musculus 
2008-06-11 | E-GEOD-106 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse uterine horns from OVX/P4/UTX 129/SvImJ WT B
Female mice used were 129/SvImJ wildtype (Jackson Lab), 10-16 weeks; of age. 14 days after ovariectomy, mice were injected; subcutaneously with progesterone dissolved in sesame oil (Sigma;; 0.2mg/0.1mL/mouse), followed by sacrifice and removal of uterine; horns at various times after injection. 8 ...
ORGANISM(S): Mus musculus 
2008-06-11 | E-GEOD-107 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse uterine horns from Hoxa-10+/+ and Hoxa-10-/- littermates
Female mice used were SvJ/129, 10-16 weeks of age; Hoxa-10+/+ and Hoxa-10-/- littermates were used in parallel experiments. 14 days after ovariectomy, mice were injected subcutaneously with progesterone dissolved in sesame oil (Sigma; 0.2mg/0.1mL/mouse), followed by sacrifice and removal of uterine ...
ORGANISM(S): Mus musculus 
2007-10-06 | E-GEOD-108 | biostudies-arrayexpress
TranscriptomicsSmall molecule activation of PKM in cancer cells induces serine auxotrophy
Proliferating tumor cells use aerobic glycolysis to support their high metabolic demands. Paradoxically, increased glycolysis is often accompanied by expression of the lower activity PKM isoform, effectively constraining lower glycolysis. Here, we report the discovery of novel PKM activators with ...
ORGANISM(S): Homo sapiens 
2012-12-20 | E-GEOD-40191 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse uterus from OVX/oil/6h/UTX 129 WT vs. Hoxa-10-/- animals
Female mice used were SvJ/129, 10-16 weeks of age; Hoxa-10+/+ and Hoxa-10-/- littermates were used in parallel experiments. 14 days after ovariectomy, mice were injected with sesame oil; (Sigma; 0.1mL/mouse), followed by sacrifice and removal of uterine; horns at 6 hours after injection. 8 uterine...
ORGANISM(S): Mus musculus 
2008-06-11 | E-GEOD-109 | biostudies-arrayexpress
UnknownAdaptive laboratory evolution of a genome-reduced Escherichia coli.
Not available
S-EPMC6389913 | biostudies-literature
UnknownMolecular consequences of the R453C hypertrophic cardiomyopathy mutation on human β-cardiac myosin motor function.
Not available
S-EPMC3732973 | biostudies-literature
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