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ProteomicsLysine acetylation of the housekeeping sigma factor enhances the activity of RNA polymerase holoenzyme
Protein lysine acetylation is one of the abundant post-translational modifications in eukaryotes, but found in prokaryotes as well. Despite the evidence of the lysine acetylation in the prokaryotic RNA polymerases (RNAPs), its function remains unrevealed. We revealed that the housekeeping sigma fact...
ORGANISM(S): Streptomyces venezuelae 
2020-05-27 | PXD015174 | Pride
Sigma factor Lysine acetylation Rna polymerase Transcription 
ProteomicsProteomic analysis reveals distinct metabolic differences between GM-CSF and M-CSF grown macrophages derived from murine bone marrow cells
Macrophages are crucial in controlling infectious agents and tissue homeostasis. Macrophages require a wide range of functional capabilities in order to fulfill distinct roles in our body, one being rapid and robust immune responses. To gain insight into macrophage plasticity and the key regulatory ...
ORGANISM(S): Mus musculus (Mouse) 
2015-08-04 | PXD002582 | Pride
Macrophage Phosphoproteins Tmt Protein identification Immunology Mass spectrometry 
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