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Characterization of preclinical models of intrahepatic cholangiocarcinoma progression that reliably recapitulate altered molecular features of the human disease. Here, we performed comprehensive gene expression profiling of cholangiocarcinoma tumors arising from bile duct inoculation of different gr...
ORGANISM(S): Rattus norvegicus 
Transcriptome analysis of embryonic cholangiocytes
Plant toxin treatment of neonatal mouse cholangiocytes
ChIp-Seq on Normal Human Cholangiocytes
Interaction with Cholangiocytes and Neutrophils
microRNA array profiling by comparing the isolated cholangiocytes from Bile Duct Ligated and Normal mouse liver
ORGANISM(S): Mus musculus 
Recent studies have demonstrated direct reprogramming of fibroblasts into a range of somatic cell types, but to date stem/progenitor cells have only been reprogrammed for the blood and neuronal lineages. We previously reported generation of induced hepatocyte-like (iHep) cells by transduction of Gat...
ORGANISM(S): Mus musculus 
Affect of Aramchol on TGFβ stimulated H69 Cholangiocytes
scRNA-seq of intrahepatic and extrahepatic (common bile duct and gallbladder) adult primary human cholangiocytes
ORGANISM(S): Homo sapiens 
Despite the impact of bile duct disorders, treatment options remain very limited. Poor access to biliary tissue and restrictions in long-term culture or significant expansion of primary cholangiocytes have posed major challenges for research in the field. These limitations have so far precluded larg...
ORGANISM(S): Homo sapiens 
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