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ProteomicsPBAF loss leads to DNA damage induced inflammatory signalling through defective G2/M checkpoint maintenance
PBRM1 is a subunit of the PBAF (SWI/SNF) chromatin remodelling complex that is mutated in approximately 40% of clear cell renal cell carcinomas (ccRCC). PBRM1 loss has been implicated in the response to immune checkpoint inhibitor (ICI) therapy in ccRCC. However, it is unclear how PBRM1 influences...
ORGANISM(S): Homo sapiens (Human) 
2022-10-13 | PXD028336 | Pride
Tmt Human Pbmr1 Cancer Ms/ms 
UnknownA Benzothiazole Derivative (5g) Induces DNA Damage And Potent G2/M Arrest In Cancer Cells.
Not available
S-EPMC5451441 | biostudies-literature
TranscriptomicsMicroarray studies on genes stimulated by RANKL in bone marrow macrophages in a cyclooxygenase-2-dependent manner
Overall goal was to look for the differentially expressed genes between receptor activator of nuclear factor kappa-B ligand (RANKL)-stimulated wild type (WT) bone marrow macrophages (BMMs) and the BMMs in which the expression or the enzyme activity of cyclooxygenase-2 (Cox2), the major enzyme for pr...
ORGANISM(S): Mus musculus 
2016-01-07 | E-GEOD-72047 | biostudies-arrayexpress
UnknownPBAF loss leads to DNA damage-induced inflammatory signaling through defective G2/M checkpoint maintenance.
Not available
S-EPMC9480851 | biostudies-literature
ProteomicsRoss Sea Surface Water Metaproteomics
We sampled the microbial community at the sea ice edge in McMurdo Sound, Ross Sea at the same location (-77.62S, 165.41E) for four weeks (as described in Wu et al 2019, Nat. Comms.). We had four sampling dates corresponding to weeks 1 to 4: December 28 2014, January 6, 15, and 22 2015. Large volumes...
ORGANISM(S): marine plankton environmental sample 
2021-09-07 | PXD022995 | Pride
Phytoplankton 
ProteomicsQuantitative phosphoproteome analyses of human macrophage-like THP-1 cells following infection with virulent Mycobacterium tuberculosis and avirulent M. bovis BCG, respectively.
In this project we conducted a comprehensive analysis of expression and global phosphorylation status of the host proteins following infection with virulent and avirulent mycobacteria. Our objective is to identify previously uncharacterized proteins of host macrophages that are specifically expresse...
ORGANISM(S): Homo sapiens (Human) 
2020-05-15 | PXD013171 | Pride
M. bovis bcg Mycobacterium tuberculosis Macrophages Proteome Phosphoproteome Mass-spectrometer 
UnknownDevelopment and Validation of a Digital (Peek) Near Visual Acuity Test for Clinical Practice, Community-Based Survey, and Research.
Not available
S-EPMC9807182 | biostudies-literature
ProteomicsOct4-FTAP - An expanded Oct4 interaction network: implications for stem cell biology, development, and disease
Control one-step purification
ORGANISM(S): Mus musculus (Mouse) 
2010-04-29 | PRD000216 | Pride
UnknownCombination chemotherapy versus temozolomide for patients with methylated MGMT (m-MGMT) glioblastoma: results of computational biological modeling to predict the magnitude of treatment benefit.
Not available
S-EPMC8280043 | biostudies-literature
UnknownClinical and histology features as predictor of severity of mucormycosis in post-COVID-19 patients: An experience from a rural tertiary setting in Central India.
Not available
S-EPMC8819781 | biostudies-literature
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