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TranscriptomicsTranscription profiling of chicken with experimentally induced myopia
One-day old white Leghorn chicks were housed in brooders with a 12 hr light:dark cycle, using General Electric chroma 50 fluorescent lighting with irradiance of approximately 50μW/cm2 at chick eye level. They received Purina Chick Chow food and water ad libitum. At one week of age and at the onset ...
ORGANISM(S): Gallus gallus 
2008-11-08 | E-GEOD-6543 | biostudies-arrayexpress
TranscriptomicsTranscriptomic comparison of osteocyte cell lines – determining their utility as models to study sex hormone regulation of skeletal function
Comparions of transcriptomes of two osteocyte cell lines under conditions that increase and decrease androgens. To study gene expression differences and the cell lines' appropriateness for studying androgen regulation of skeletal function
ORGANISM(S): Mus musculus 
2026-09-01 | E-MTAB-16564 | biostudies-arrayexpress
TranscriptomicsBeta cell overexpression of HSD11B1 in high fat fed mice
To model the potential diabetogenic effects of higher level of HSD11B1 in b-cells of the pancreas in vivo, we created a transgenic model overexpressing HSD11B1 under the mouse insulin I promoter (MIP-HSD1) in diabetes-prone C57Bl/KsJ mice. KsJ wild type and MIP-HSD1 heterozygous mice have been high ...
ORGANISM(S): Mus musculus 
2011-06-30 | E-GEOD-23161 | biostudies-arrayexpress
UnknownNeuronal SNAP-23 is critical for synaptic plasticity and spatial memory independently of NMDA receptor regulation.
Not available
S-EPMC10165271 | biostudies-literature
UnknownThe Spirodela polyrhiza genome reveals insights into its neotenous reduction fast growth and aquatic lifestyle.
Not available
S-EPMC3948053 | biostudies-literature
TranscriptomicsCanonical Nlrp3 inflammasome activation links systemic age-related inflammation with functional decline
This experiment was performed to analyze the contribution of NLRP3 inflammasome activation to age-related changes in hippocampal RNA. The hypothesis was that decreased inflammasome activation would reduce hippocampal inflammation. Results indicate that inflammasome knockout animals are protected fr...
ORGANISM(S): Mus musculus 
2013-09-05 | E-GEOD-43034 | biostudies-arrayexpress
TranscriptomicsEffects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice
Calorie restriction (CR) is the most robust non-genetic intervention to universally delay the onset of age-related diseases and extend mean and maximum lifespan. However, species, strain, sex, diet, age of onset, and level of CR are emerging as important variables to consider for a successful CR res...
ORGANISM(S): Mus musculus 
2016-06-27 | E-GEOD-81959 | biostudies-arrayexpress
UnknownInternational Impact of COVID-19 on the Diagnosis of Heart Disease.
Not available
S-EPMC7836433 | biostudies-literature
UnknownPrediction of disability-free survival in healthy older people.
Not available
S-EPMC9213595 | biostudies-literature
UnknownEffect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly.
Not available
S-EPMC6289056 | biostudies-literature
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