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ProteomicsMulti-region proteomics of synaptosomes and cytosolic fractions of Chrdl1 KO and WT mouse brains
This dataset contains proteomic analyses of synaptosomal and cytosolic fractions isolated from the cortex and hippocampus of adult male wild-type (WT) and Chordin-like 1 (Chrdl1) knockout (KO) mice. The study was designed to investigate how loss of Chrdl1 affects the proteomic profile of these two b...
ORGANISM(S): Mus musculus (Mouse) 
2026-08-19 | PXD082639 | Pride
Hippocampus Cytosol fraction Cortex Synaptosome Chrdl1 ko 
GenomicsTranscriptome of the visual cortex in WT or Chrdl1 KO mice at post-natal day 14
Transcriptome of the visual cortex in WT or Chrdl1 KO mice at post-natal day 14
PRJNA427396 | ENA
TranscriptomicsTranscriptome of the visual cortex in WT or Chrdl1 KO mice at post-natal day 14
Chrdl1, a BMP antagonist, is an astrocyte-secreted factor that promotes synapse maturation in the upper layers of the visual cortex at P14. We analyzed the transcriptome of the visual cortex of WT and Chrdl1 KO mice at P14 in order to determine if genes related to BMP signaling, astrocyte developmen...
ORGANISM(S): Mus musculus 
2018-10-29 | GSE108483 | GEO
UnknownOcular Manifestations of Chordin-like 1 Knockout Mice.
Not available
S-EPMC7415553 | biostudies-literature
UnknownAstrocyte-Secreted Chordin-like 1 Drives Synapse Maturation and Limits Plasticity by Increasing Synaptic GluA2 AMPA Receptors.
Not available
S-EPMC6382071 | biostudies-literature
TranscriptomicsChromatin immunoprecipitation of human PolII and SUZ12 proteins in embryonic stem cells
Polycomb group proteins are essential for early development in metazoans but their contributions to human development are not yet well understood. We have mapped the Polycomb Repressive Complex 2 (PRC2) subunit Suz12 across the entire non-repeat portion of the genome in human embryonic stem (ES) cel...
ORGANISM(S): Homo sapiens 
2006-06-14 | E-WMIT-7 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of Oct4, Nanog and Suz12 in human and mouse embryonic stem cells to identify promoters for miRNAs
Understanding the transcriptional regulatory circuitry responsible for pluripotency and self-renewal in embryonic stem (ES) cells is fundamental to understanding human development and realizing the therapeutic potential of these cells. The transcription factor Oct4 and the chromatin-modifying Polyc...
ORGANISM(S): Homo sapiens 
2010-12-01 | E-TABM-365 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of Oct4 in human embyonic stems cells
Chip-CHIP of human Oct4 from human embryonic stem cells
ORGANISM(S): Homo sapiens 
2008-08-01 | E-MEXP-1687 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation genome wide binding sites of Oct4, Sox2, and Nanog in human
The transcription factors Oct4, Sox2, and Nanog have essential roles in early development and are required for the propagation of undifferentiated embryonic stem (ES) cells in culture. To gain insights into transcriptional regulation of human ES cells, we have identified Oct4, Sox2, and Nanog target...
ORGANISM(S): Homo sapiens 
2005-09-23 | E-WMIT-5 | biostudies-arrayexpress
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