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TranscriptomicsTranscriptional profiling of response to acute caloric restriction in liver and fat of pigs differing in feed efficiency
Residual feed intake (RFI) is a measure of feed efficiency, where low RFI denotes high feed efficiency. Caloric restriction (CR) is associated with feed efficiency in livestock species and to human health benefits such as longevity and cancer prevention. We have developed pig lines that differ in RF...
ORGANISM(S): Sus scrofa 
2010-01-10 | E-GEOD-18359 | biostudies-arrayexpress
TranscriptomicsGene expression arrays comparing Kluyveromyces lactis wild-type a cells to MATa2 knock-out a cells and wild-type alpha cells to MATalpha2 knock-out alpha cells
We examine how different transcriptional network structures can evolve from a common, ancestral network. We show that regulatory protein modularity, conversion of one cis-regulatory sequence to another, distribution of binding energy among protein-protein and protein-DNA interactions, and exploitati...
ORGANISM(S): Kluyveromyces lactis 
2012-06-29 | E-GEOD-39027 | biostudies-arrayexpress
TranscriptomicsNanostring Profiling of the GBM Xenoline JX14 grown in monoculture in PDX or PSX media, or in triculture in triculture with macrophages and astrocytes in PSX
Nanostring microarray of the GBM Xenoline JX14P at 3 separate passages grown in PDX media (monoculture), PSX media (monoculture), or PSX media (indirect triculture).
ORGANISM(S): Homo sapiens 
2025-04-01 | E-MTAB-14811 | biostudies-arrayexpress
ProteomicsIdentification of regulators of polyploidization presents therapeutic targetsfor treatment of AMKL
Wen Q, Goldenson B, Silver SJ, Schenone M, Dancik V, Huang Z, Wang LZ, Lewis TA, An WF, Li X, Bray MA, Thiollier C, Diebold L, Gilles L, Vokes MS, Moore CB, Bliss-Moreau M, Verplank L, Tolliday NJ, Mishra R, Vemula S, Shi J, Wei L, Kapur R, Lopez CK, Gerby B, Ballerini P, Pflumio F, Gilliland DG, Go...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2014-01-27 | MSV000078536 | MassIVE
UnknownMutational Spectrum, Copy Number Changes, and Outcome: Results of a Sequencing Study of Patients With Newly Diagnosed Myeloma.
Not available
S-EPMC6485456 | biostudies-literature
TranscriptomicsExpression data from LCM-captured Zea mays root cells after challenge with Meloidogyne incognita
The differentiation of specialized feeding sites in Zea mays root cells in response to nematode infestation involves substantial cellular reprogramming of host cells that is not well characterized at the molecular level. Expression data was generated from Zea mays root cells undergoing giant cell fo...
ORGANISM(S): Zea mays 
2012-04-27 | E-GEOD-37556 | biostudies-arrayexpress
TranscriptomicsExpression data from LCM-captured Arabidopsis root cells after challenge with Meloidogyne incognita
The differentiation of specialized feeding sites in Arabidopsis root cells in response to nematode infestation involves substantial cellular reprogramming of host cells that is not well characterized at the molecular level. Expression data was generated from Arabidopsis root cells undergoing giant c...
ORGANISM(S): Arabidopsis thaliana 
2012-04-26 | E-GEOD-37553 | biostudies-arrayexpress
TranscriptomicsComparison between NuGEN's WT-Ovation Pico and One-Direct Amplification Systems
Differential gene expression between groups of homogenous cell types is a biological question whose time has come. RNA can be extracted from small numbers of cells, such as those isolated by laser capture microdissection, but the small amounts obtained often require amplification to enable whole ge...
ORGANISM(S): Arabidopsis thaliana 
2010-06-08 | E-GEOD-21981 | biostudies-arrayexpress
MetabolomicsClock regulation of metabolites reveals coupling between transcription and metabolism
The circadian clock is intricately connected with metabolism, however the precise details of these connections are incomplete. Here we used high temporal resolution metabolite profiling to determine circadian regulation of mouse liver and cell autonomous metabolism. In mouse liver, we found ~50% of ...
2017-04-05 | MTBLS292 | MetaboLights
TranscriptomicsGenome-Wide Specificity of DNA-Binding, Gene Regulation, and Chromatin Remodeling by TALE- and CRISPR/Cas9-Based Transcription Factors
Synthetic DNA-binding proteins have found broad application in gene therapies and as tools for interrogating biology. Engineered proteins based on the CRISPR/Cas9 and TALE systems have been used to alter genomic DNA sequences, control transcription of endogenous genes, and modify epigenetic states. ...
ORGANISM(S): Homo sapiens 
2015-05-27 | E-GEOD-68341 | biostudies-arrayexpress
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