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ModelsKosinsky2018 - Radiation and PD-(L)1 treatment combinations
This is a quantitative systems pharmacology (QSP) model that describes key elements of the cancer immunity cycle and the tumor microenvironment, tumor growth, as well as dose-exposure-target modulation features. The model describes the synergistic kinetic effects underlying immune cell interactions ...
2024-09-02 | BIOMD0000000863 | BioModels
Immuno-oncology 
ModelsChaudhury2020 - First order expansion model of CAR-T cell and tumour kinetics
This ordinary differential equation model of the cellular kinetics and pharmacodynamics of CAR-T cell therapy is described in the publication: Chaudhury, A., Zhu, X., Chu, L., Goliaei, A., June, C., Kearns, J. and Stein, A., 2020. Chimeric Antigen Receptor T Cell Therapies: A Review of Cellular Kine...
2021-09-11 | MODEL2109110005 | BioModels
ModelsChaudhury2020 - Lotka-Volterra mathematical model of CAR-T cell and tumour kinetics
This ordinary differential equation model of the cellular kinetics and pharmacodynamics of CAR-T cell therapy is described in the publication: Chaudhury, A., Zhu, X., Chu, L., Goliaei, A., June, C., Kearns, J. and Stein, A., 2020. Chimeric Antigen Receptor T Cell Therapies: A Review of Cellular Kine...
2024-09-02 | BIOMD0000001024 | BioModels
Immuno-oncology 
ModelsChaudhury2020 - EC50 expansion and killing mathematical model of CAR-T cell and tumour kinetics
This ordinary differential equation model of the cellular kinetics and pharmacodynamics of CAR-T cell therapy is described in the publication: Chaudhury, A., Zhu, X., Chu, L., Goliaei, A., June, C., Kearns, J. and Stein, A., 2020. Chimeric Antigen Receptor T Cell Therapies: A Review of Cellular Kine...
2024-09-02 | BIOMD0000001025 | BioModels
Immuno-oncology 
TranscriptomicsNOT2 proteins promote Pol II-dependent transcription and interact with multiple miRNA biogenesis factors in Arabidopsis
MicroRNAs (miRNAs) play key regulatory roles in numerous developmental and physiological processes in animals and plants. The elaborate mechanism of miRNA biogenesis involves transcription and multiple processing steps. Here, we report the identification of a pair of evolutionarily conserved NOT2_3_...
ORGANISM(S): Arabidopsis thaliana 
2013-01-30 | E-GEOD-42901 | biostudies-arrayexpress
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