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TranscriptomicsRegulation of Transcription Termination by Glucosylated Hydroxymethyluracil, Base J, in L. major and T. brucei
Base J, β-D-glucosyl-hydroxymethyluracil, is an epigenetic modification of thymine in the nuclear DNA of flagellated protozoa of the order Kinetoplastida. J is enriched at sites involved in RNA Polymerase (RNAP) II initiation and termination. We have previously demonstrated a role of J in regulating...
ORGANISM(S): Trypanosoma brucei 
2015-05-18 | E-GEOD-57621 | biostudies-arrayexpress
GenomicsJBP1-seq: a fast and efficient method for genome-wide profiling of 5hmC
We developed a novel approach, J-binding protein 1 sequencing (JBP1-seq), that combines the benefits of an improved recombinant JBP1 protein, Nextera-based library construction, and nextgeneration sequencing (NGS) for genome-wide profiling of 5-hydroxymethylcytosine (5hmC). Compared with the orig...
ORGANISM(S): Homo sapiens 
2014-11-26 | E-GEOD-61193 | biostudies-arrayexpress
UnknownCapture Rate of V(D)J Sequencing for Minimal Residual Disease Detection in Multiple Myeloma.
Not available
S-EPMC9179004 | biostudies-literature
TranscriptomicsProfiling Chung rat model for neuropathic pain
This program addresses the gene signature associated with DRG in the Chung rat model for neuropathic pain. The Chung neuropathic pain profiling data was analyzed by identifying genes that were up- and down-regulated at selected p value and fold change in DRG of the Sprague Dawley rats following spin...
ORGANISM(S): Rattus norvegicus 
2013-03-22 | E-GEOD-38038 | biostudies-arrayexpress
UnknownDirect experimental observation of the molecular J eff = 3/2 ground state in the lacunar spinel GaTa4Se8.
Not available
S-EPMC5627251 | biostudies-literature
UnknownCamphoratins A-J, potent cytotoxic and anti-inflammatory triterpenoids from the fruiting body of Taiwanofungus camphoratus.
Not available
S-EPMC2993773 | biostudies-literature
MetabolomicsCharacteristics of steroid hormones in systemic lupus erythematosus revealed by GC/MS-based metabolic profiling

Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with a remarkable predominance in female, suggesting that steroid hormones may be involved in the pathogenesis. Herein, more than 70 kinds of steroids in urine were detected by gas chromatography/mass spectrometry (GC/MS) to reve...

2023-07-28 | MTBLS7766 | MetaboLights
UnknownCoenzyme Q10 alleviates tacrolimus-induced mitochondrial dysfunction in kidney.
Not available
S-EPMC6902707 | biostudies-literature
TranscriptomicsA study of the differentiation of Murine ES cells [Scl+/hCD4 ES cells (Chung et al., 2002)] into hemangioblasts
Molecular mechanisms that regulate the generation of hematopoietic and endothelial cells from mesoderm are poorly understood. To define the underlying mechanisms, we compared gene expression profiles between embryonic stem (ES) cell-derived hemangioblasts (Blast-Colony-Forming Cells, BL-CFCs) and th...
ORGANISM(S): Mus musculus 
2007-01-25 | E-GEOD-6835 | biostudies-arrayexpress
UnknownRefining the clinical phenotype of Okur-Chung neurodevelopmental syndrome.
Not available
S-EPMC5874396 | biostudies-literature
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