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ProteomicsDynamic Assembly of the Cytosolic Iron-Sulfur Cluster Biogenesis Machinery Requires Iron-Sulfur Cluster Incorporation of CIAO3
Cytosolic iron-sulfur (Fe-S) cluster assembly (CIA) pathway delivers Fe-S clusters to nuclear and cytosolic Fe-S proteins involved in essential cellular functions. This delivery process is regulated by availability of iron and oxygen, but it remains unclear how CIA components orchestrate the cluster...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-11-16 | MSV000088394 | MassIVE
ProteomicsIron-Regulated Assembly of the Cytosolic Iron-Sulfur Cluster Biogenesis Machinery
The cytosolic iron-sulfur (Fe-S) cluster assembly (CIA) pathway delivers Fe-S clusters to nuclear and cytosolic Fe-S proteins involved in essential cellular functions. Although the delivery process is regulated by the availability of iron and oxygen, it remains unclear how CIA components orchestrate...
ORGANISM(S): Homo Sapiens 
2022-06-06 | PXD033557 | panorama
UnknownElectroacupuncture stimulating Zusanli (ST36), Sanyinjiao (SP6) in mice with collagen-induced arthritis leads to adenosine A2A receptor-mediated alteration of p38α mitogen-activated protein kinase signaling and inhibition of osteoclastogenesis.
Not available
S-EPMC10623259 | biostudies-literature
TranscriptomicsGene expression profile in Shh-expressing cells of hair follicles in mouse during CIA
Chemotherapy-induced alopecia (CIA) is a major unsolved adverse effect in clinical oncology. In previous studies, we proved the Sonic hedgehog(Shh) signaling pathway is a major target of cyclophosphamide (CYP). However, how CYP suppresses Shh gene remains unknown. In this study, we isolated Shh-expr...
ORGANISM(S): Mus musculus 
2026-03-16 | GSE277257 | GEO
UnknownGancao Nourishing-Yin decoction combined with methotrexate in treatment of aging CIA mice: a study based on DIA proteomic analysis.
Not available
S-EPMC9883815 | biostudies-literature
GenomicsGene expression profile in Shh-expressing cells of hair follicles in mouse during CIA
Gene expression profile in Shh-expressing cells of hair follicles in mouse during CIA
PRJNA1161602 | ENA
TranscriptomicsHK_CIA_experiment
In previous studies, we identified the fungal macrocyclic lactone (S)-curvularin (SC) as an anti-inflammatory agent using a screening system detecting inhibitors of the Janus kinase/signal transducer and activator of transcription pathway. The objective of the present study was to investigate whethe...
ORGANISM(S): Mus musculus 
2012-09-21 | E-MEXP-3180 | biostudies-arrayexpress
UnknownThe cytosolic iron-sulfur cluster assembly (CIA) pathway is required for replication stress tolerance of cancer cells to Chk1 and ATR inhibitors.
Not available
S-EPMC8639742 | biostudies-literature
MetabolomicsCollagen induced arthritis in dba/1j mice associates with oxylipin changes in plasma
Oxylipins play important roles in various biological processes and are considered as mediators of inflammation for a wide range of diseases such as rheumatoid arthritis (RA). The purpose of this research was to study differences in oxylipin levels between a widely used collagen-induced arthritis (CI...
2015-11-04 | MTBLS243 | MetaboLights
ProteomicsProtein expression of Isolated B cells from splenocytes in collagen-induced arthritis (CIA) model between Wildtype (C57BL/6) and Stinggt/gt mice.
The pathogenesis of rheumatoid arthritis (RA) is complicated and involves both innate and adaptive immunity [5]. The innate immunity such as macrophages or fibroblast-like synoviocytes (FLS) in the synovium can generate inflammatory mediators, including TNF-α, IL-1, IL-6, IL-17, IFN-γ, and chemo kin...
ORGANISM(S): Mus musculus (Mouse) 
2020-06-26 | PXD018652 | Pride
Quantitative proteomics Sting Collagen-induced arthritis 
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