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ProteomicsQuantitativeCancerProteomicAtlas1.2 observable peptides
This dataset contain evidences of observability of QCPA (v1.2) peptides, in whole cell tryptic proteome background.
ORGANISM(S): Homo sapiens (Human) 
2022-10-12 | PXD034653 | Pride
Human qcpa phosphorylation synthetic 
ProteomicsIntracellular zinc chaperones in plants
Metal availability is tightly regulated within cells through metal homeostasis to prevent cytotoxicity from excess and protein inactivity from deficiency. Limited bioavailability of essential metals in soil can negatively impact crop health and yield. A plant zinc (Zn)-homeostatic mechanism involvin...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-08-21 | PXD042911 | Pride
A.thaliana root tmt16plex proteomics chaperones zinc 
ProteomicsSignal peptide-independent secretion of keratin-19 by pancreatic cancer cells
T cells exclusion precludes checkpoint inhibition efficacy in pancreatic ductal adenocarcinoma (PDA) and is mediated by the interaction between T cell CXCR4, and its ligand CXCL12, which is complexed to keratin-19 (KRT19) on the surface of PDA cells. KRT19 secretion is essential to this process but ...
ORGANISM(S): Homo sapiens (Human) 
2025-06-16 | PXD051583 | Pride
Keratin19  pancreatic ductal adenocarcinoma  immunoprecipitation  ingel 
ProteomicsBXPC3 and PANC1 secretome analysis (SEC61-biotin transferase system)
Cells expressing a ER resident biotin trasferase (SEC61 fusion) secreted biotinylated protein in the culture medium. This project nominated bona fide secreted factors.
ORGANISM(S): Homo sapiens (Human) 
2025-06-16 | PXD057028 | Pride
Secretome bxpc3 panecreatic ductal adenocarcinoma 
ProteomicsTranslesion DNA synthesis polymerase κ is essential to a carcinogen-induced nucleolar stress response
Goal of the experiment was to identify putative binding proteins enriched using the iPond technique.
ORGANISM(S): Homo sapiens (Human) 
2024-07-25 | PXD038641 | Pride
Human ipond dna repair polymerase 
ProteomicsMARK2/MARK3 kinases are catalytic co-dependencies of YAP/TAZ in human cancer
Human cancer is often caused by dysfunctional developmental pathways, but such mechanisms do not always present clear opportunities for therapeutic intervention. This is exemplified by the Hippo tumor suppressor pathway, which is comprised of a kinase module that restrains the function of YAP/TAZ tr...
ORGANISM(S): Homo sapiens (Human) 
2024-07-25 | PXD044829 | Pride
Phosphorylation hippo pathway mark2/3 
ProteomicsAldehydes alter TGF-b signaling and induce obesity and cancer
Obesity and fatty liver diseases—metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH)—affect over one-third of the global population and are exacerbated in individuals with reduced functional aldehyde dehydrogenase 2 (ALDH2), ob...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055145 | Pride
Sptbn1 aldehydes 4-hydroxynonenal 
ProteomicsHigh Dynamic Range peptide mass spectrometry using segmented precursor ions accumulation - Plasma
Limited sensitivity and depth of proteome sampling in experiments using Data-Dependent Acquisition (DDA) mass spectrometry are usually attributed to insufficient rate of fragmentation spectra acquisition relative to the number of co-eluting potential targets. Here we demonstrated that limited sensit...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
MSV000099211 | MassIVE
ProteomicsHigh Dynamic Range peptide mass spectrometry using segmented precursor ions accumulation - SILAC
Limited sensitivity and depth of proteome sampling in experiments using Data-Dependent Acquisition (DDA) mass spectrometry are usually attributed to insufficient rate of fragmentation spectra acquisition relative to the number of co-eluting potential targets. Here we demonstrated that limited sensit...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000099210 | MassIVE
ProteomicsHigh Dynamic Range peptide mass spectrometry using segmented precursor ions accumulation - Method Benchmarking
Limited sensitivity and depth of proteome sampling in experiments using Data-Dependent Acquisition (DDA) mass spectrometry are usually attributed to insufficient rate of fragmentation spectra acquisition relative to the number of co-eluting potential targets. Here we demonstrated that limited sensit...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000099208 | MassIVE
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