Sort   by:  
 Page size 
TranscriptomicsThe glomerular circadian clock temporally regulates basement membrane dynamics and glucocorticoid response. Cultured podocyte cells circadian clock
Kidney physiology has diurnal variation and abnormal circadian rhythm is associated with kidney disease. However, it is not known whether glomeruli, the filtering units in the kidney, are under circadian control. We therefore investigated core circadian clock components in cultered podocyte cells, t...
ORGANISM(S): Mus musculus 
2025-04-22 | E-MTAB-13459 | biostudies-arrayexpress
TranscriptomicsCopy number variation in the bovine genome
Copy number variations (CNVs), which represent a significant source of genetic diversity in mammals, are currently being associated with phenotypes of clinical relevance, mostly in humans and mice. Notwithstanding, little is known about the extent of CNV that contributes to genetic variation in catt...
ORGANISM(S): Bos taurus 
2010-04-22 | E-GEOD-18174 | biostudies-arrayexpress
TranscriptomicsThe glomerular circadian clock temporally regulates basement membrane dynamics and glucocorticoid response
Kidney physiology has diurnal variation and abnormal circadian rhythm is associated with kidney disease. However, it is not known whether glomeruli, the filtering units in the kidney, are under circadian control. We therefore investigated core circadian clock components in glomeruli, together with t...
ORGANISM(S): Mus musculus 
2024-09-20 | E-MTAB-13457 | biostudies-arrayexpress
TranscriptomicsCircadian regulation of gene expression in the coral algal endosymbiosis
Despite their early evolutionary divergence, reef-building corals exhibit complex circadian responses to diurnal, lunar and annual changes in the conditions around them. Understanding circadian regulation in reef-building corals is, however, complicated by the presence of photosynthetic endosymbiont...
ORGANISM(S): Acropora millepora 
2011-04-20 | E-GEOD-21658 | biostudies-arrayexpress
TranscriptomicsSomatic mosaicism for copy number variation in differentiated human tissues
Genetic variation is responsible for the generation of phenotypic diversity, including susceptibility to disease. Two major types of variation are known: single nucleotide polymorphisms (SNPs) and a more recently discovered structural variation, involving changes in copy number (CNVs) of kilobase- t...
ORGANISM(S): Homo sapiens 
2008-09-16 | E-GEOD-9598 | biostudies-arrayexpress
GenomicsNatural genetic variation perturbs collaborative transcription factor binding required for enhancer selection and function
Natural genetic variation between two mouse strains was used as a natural mutagenesis screen to test various aspects of the proposed model for enhancer selection and function. Chromatin marks H3K4me2, H3K27Ac, and transcription factors PU.1, C/EBPa, and p65 were assessed by ChIP-Seq and GRO-Seq and ...
ORGANISM(S): Mus musculus 
2013-10-15 | E-GEOD-46494 | biostudies-arrayexpress
TranscriptomicsCircadian regulation in rat abdominal adipose tissue
Circadian rhythms are oscillations with a periodicity of 24 hours that are controlled by an endogenous clock and are observed in virtually all aspects of mammalian function from expression of genes to complex physiological processes. The master clock is present in the suprachiasmatic nucleus (SCN) i...
ORGANISM(S): Rattus norvegicus 
2010-03-09 | E-GEOD-20635 | biostudies-arrayexpress
ProteomicsCircadian Gene Expression in Mouse Renal Proximal Tubule
Circadian variability in kidney function has long been recognized but is often ignored as a potential confounding variable in in vivo physiological experiments. To provide a guide for physiological studies on the kidney proximal tubule, we have now created a data resource consisting of expression le...
ORGANISM(S): Mus musculus (Mouse) 
2023-04-10 | PXD039006 | Pride
Circadian variation Proteomics Proximal tubule Transcriptomics 
ProteomicsDirect evaluation of metabolic rhythms from quantitative circadian proteomics revealed rampant post-transcriptional regulation by Chlamydomonas clock
Temporal dynamics in an organism's behavior, physiology, metabolism, and biochemistry over the course of 24 hours are governed by an inherent cellular clock. Transcriptomic studies revealed that the clock is governed by intricate transcriptional and translational feedback loops(TTFLs) involving dail...
ORGANISM(S): Chlamydomonas reinhardtii 
2025-05-27 | PXD043839 | Pride
Post-transcriptional regulations Swath-ms Proteomics C. reinhardtii Circadian clock 
TranscriptomicsTranscription profiling of Macaca mulatta adrenal gland over a 24 hour period to investigate circadian regulation of gene expression
Circadian regulation of gene expression in central and peripheral tissue has been studied in mice. The biomedical implications of this findings led us to the development of a model in which to study the circadian mechanisms underlying primate physiology. The objective of this experiment has been to ...
ORGANISM(S): Macaca mulatta 
2007-10-05 | E-GEOD-2703 | biostudies-arrayexpress
Sort   by:  
 Page size