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UnknownMicroRNA signature of cis-platin resistant vs. cis-platin sensitive ovarian cancer cell lines.
Not available
S-EPMC3205057 | biostudies-literature
GenomicsMolecular mechanisms associated with cis-platin intrinsic resistance in early drug-tolerant persister cells of lung adenocarcinoma cell lines
Molecular mechanisms associated with cis-platin intrinsic resistance in early drug-tolerant persister cells of lung adenocarcinoma cell lines
PRJNA879192 | ENA
UnknownInteraction of Half Oxa-/Half cis-Platin Complex with Human Superoxide Dismutase and Induced Reduction of Neurotoxicity.
Not available
S-EPMC6231183 | biostudies-literature
TranscriptomicsMolecular mechanisms associated with cis-platin intrinsic resistance in early drug-tolerant persister cells of lung adenocarcinoma cell lines
To investigate the mechanism associated with cis-platin intrinsic resistance, we established a model of early drug-tolerant persister cells by exposing lung adenocarcinoma cell lines to the drug for 24 h. Then, we analyzed the transcriptome using RNA-seq from 4 different lung adenocarcinoma cell lin...
ORGANISM(S): Homo sapiens 
2023-11-03 | GSE213102 | GEO
UnknownTreatment of nasopharyngeal carcinoma cells with the histone-deacetylase inhibitor abexinostat: cooperative effects with cis-platin and radiotherapy on patient-derived xenografts.
Not available
S-EPMC3949989 | biostudies-literature
TranscriptomicsmiRNA signature for cis-platinum resistant ovarian cancer cells A2780
We have done the analysis of cis-platinum susceptible and resistant ovarian cancer cell lines (A2780). After having passed sample QC on the Bioanalyser2100 and RNA measurement on the Nanodrop instrument, the samples were
labelled using the miRCURYM-^Y Hy3M-^Y/Hy5M-^Y power labeling kit and hybrid...
ORGANISM(S): Homo sapiens 
2011-04-15 | E-MEXP-3141 | biostudies-arrayexpress
TranscriptomicsProtection of TLR5 agonist, CBLB502, against cisplatin treated mouse liver and kidney
TLR5 agonist CBLB502 has been reported playing protective effects again IR, Here we find CBLB502 might protect cis-platin induced liver and kidney damages.
ORGANISM(S): Mus musculus 
2023-08-01 | GSE210655 | GEO
TranscriptomicsExpression data identifying hypermethylated genes associated with acquired cisplatin resistance
Treatment-related DNA hypermethylation may play a role in creating drug resistant phenotypes by inactivating genes that are required for cytotoxicity, but there have been no genome-wide studies to systematically investigate methylation of individual genes following exposure to chemotherapy. We used ...
ORGANISM(S): Homo sapiens 
2010-04-12 | E-GEOD-19397 | biostudies-arrayexpress
ProteomicsDown-regulation of Rab 5C-dependent Endocytosis and Glycolysis in Cisplatin-resistant Ovarian Cancer Cell Lines
Drug resistance poses a major challenge to ovarian cancer treatment. Understanding mechanisms of drug resistance is important for finding new therapeutic targets. In the present work, a cisplatin-resistant ovarian cancer cell line A2780-DR was established with a resistance index of 6.64. The cellula...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080724 | MassIVE
TranscriptomicsExpression Profiles of PMH treated with 7M-BM-5M of the genotoxic compound cisplatin
The transcriptomic changes induced in primary mouse hepatocytes (C57BL/6 ) by 7M-BM-5M of cisplatin after treatment for 24 and 48h The study investigated differential gene expression in PMH mRNA following 24 and 48 hours of exposure to 7M-BM-5M of cisplatin and its solvent. Three biological replic...
ORGANISM(S): Mus musculus 
2013-12-05 | E-GEOD-38123 | biostudies-arrayexpress
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